LOCALLY ADVANCED UROTHELIAL CARCINOMA
Clinical trials for LOCALLY ADVANCED UROTHELIAL CARCINOMA explained in plain language.
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New drug cocktail aims to shrink tough bladder tumors
Disease control Recruiting nowThis early-phase trial tests a combination of two drugs, cabozantinib and enfortumab vedotin, in people with advanced bladder cancer that has spread or cannot be removed. The goal is to find the best dose and see if the combo is safe and shrinks tumors. About 32 adults who have a…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated May 17, 2026 02:06 UTC
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Tailor-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors. The goal is to see if this combination is safe and helps the immune system fight cancer more effectively. A…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New combo aims to outsmart resistant bladder cancer in phase 3 trial
Disease control Recruiting nowThis phase 3 trial tests whether combining two drugs—pembrolizumab (an immunotherapy) and sacituzumab govitecan (a targeted chemo)—works better than standard chemotherapy for people with advanced bladder cancer that no longer responds to initial immunotherapy. About 320 adults wi…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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Engineered immune cells take on tough bladder cancers
Disease control Recruiting nowThis early-stage trial tests a new treatment made from donor immune cells (CAR-NK cells) designed to attack two targets on bladder cancer cells. It is for adults with advanced bladder cancer that has not responded to standard therapies. The main goals are to check safety and see …
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Beijing Biotech • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Can surgery lock in cancer control? new trial tests consolidative therapy
Disease control Recruiting nowThis study looks at whether adding surgery to remove remaining cancer spots can help people with advanced bladder cancer stay cancer-free longer. Participants first receive drug therapy to control the disease, then undergo surgery to remove the primary tumor and any remaining spr…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
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Cancer patients may soon get immunotherapy at home – no more long clinic trips!
Symptom relief Recruiting nowThis study looks at whether giving the cancer drug nivolumab as a shot at home is as good as getting it at the clinic. About 50 adults with various cancers will try both ways to see which they prefer and how it affects their quality of life. The goal is to reduce the time, cost, …
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 17, 2026 01:59 UTC