University Of Missouri-columbia

This study planned to test whether a 14-day ketogenic diet before heart bypass surgery could reduce confusion and memory loss in adults aged 60 and older. The diet was thought to lower brain inflammation and improve brain cell health. However, the study was withdrawn before any p…

This study compares remote monitoring to standard in-person follow-up for adults who had wrist fracture surgery. About 160 participants will use a secure app or attend clinic visits. Researchers will measure arm function, quality of life, and complication rates over 6 months to s…

This study tests whether giving a mix of methadone, dexmedetomidine, and ketamine during complex spine surgery can reduce pain and the need for opioid painkillers afterward. About 248 adults having surgery on three or more spine levels will take part. The goal is to see if this c…

This study tests an intensive group physical therapy program for children aged 7-17 with cerebral palsy who can walk. The program focuses on improving muscle strength, walking speed, and daily activities like climbing stairs. Researchers will measure changes in strength, balance,…

This study tests whether virtual reality (VR) meditation can improve sleep and reduce anxiety in people with chronic pain and insomnia. About 30 adults with both conditions for at least 6 months will use VR meditation and track their sleep, pain, and mood. The goal is to see if t…

This study tests if giving a standard amount of IV fluids before surgery can prevent low blood pressure after anesthesia in people having a cystoscopy. About 100 adults will take part. The goal is to see if this simple step reduces the risk of blood pressure drops during the proc…

This study is testing whether a Mediterranean-style low-carb diet that reduces calories can lower insulin and testosterone levels in overweight or obese women with insulin resistance. Eight premenopausal women aged 21-45 will follow the diet to lose about 5% of their body weight.…

This early-stage study tests whether sirolimus, an FDA-approved drug, can improve blood flow to the brain in healthy adults aged 45-65. Some participants carry a gene (APOE4) that raises Alzheimer's risk, while others do not. The goal is to see if the drug affects brain blood flo…

This study looks at whether wearable technology, like the Oura Ring, can help measure stress and burnout in nurses. Fifty nurses from intensive care and surgical units will wear the rings and fill out surveys for 10 weeks. The goal is to see if workload and stress levels are link…

This study looks at why overweight adults with sleep apnea have a higher risk of blood sugar problems and diabetes. Researchers will compare people with and without sleep apnea, and test whether using a CPAP machine or just extra oxygen at night can improve how the body handles s…

This study looks at how eating pulses like beans and lentils changes the bacteria in your gut and affects your appetite. Researchers will measure gut microbes, appetite hormones, and other health markers in 44 overweight adults. Participants will eat a special diet and provide bl…

This study aimed to see if adding telehealth sessions to in-person physical therapy helps children with moderate to severe disabilities improve daily skills at home more than in-person therapy alone. It planned to include children ages 2 to 17 and measure changes in function and …

This study looks at how insulin in the brain changes blood flow and nerve signals in healthy adults aged 18-45. Researchers will measure blood flow in the brain and legs, as well as nerve activity. The goal is to understand basic body functions, not to treat any disease.

This study looks at how high-protein drinks affect certain blood cells (monocytes and platelets) that may play a role in heart disease. Ten healthy adults will drink either a low-protein, high-protein, or leucine-added meal, and researchers will check their blood for changes in c…

This study looks at how cannabis use changes the amount of anesthesia needed during lumbar spine surgery and how it affects inflammation and wound healing. Researchers will compare 210 adults who use cannabis with those who do not, measuring anesthetic doses and blood markers of …

This study looks at why some people with obesity have normal blood sugar while others do not. Researchers will measure how much sugar fat and muscle tissues take up in people with and without insulin resistance. About 90 adults will participate, including lean and obese individua…