University Of Missouri-columbia

This study tested a program designed with Cherokee community members to help reduce heart disease risk. Researchers worked with 42 Cherokee adults to create and try out activities that strengthen community ties and share Cherokee history. The goal was to see if these activities c…

This study tested whether amiloride, a drug that blocks a salt channel in blood vessels, can improve artery stiffness in overweight adults with insulin resistance. 137 men and women (pre- and post-menopausal) participated. The goal was to see if the drug could help control a key …

This study tested a new system called the Opioid Rapid Response System (ORRS) that uses a smartphone app to train and alert citizens to respond to opioid overdoses with naloxone. Over 700 adults from communities using the PulsePoint app took part. The goal was to see if the app i…

This study looked at whether cognitive behavioral therapy (CBT) for insomnia could also help reduce pain and improve sleep in women with fibromyalgia. 131 women with both conditions participated. The goal was to see if better sleep leads to less pain and changes in how the brain …

This study tested whether a cognitive strategy training program, delivered remotely, is feasible and helpful for people with long COVID who experience brain fog. 65 participants were enrolled. The program aimed to improve their ability to perform everyday activities and their qua…

This study tested a special thinking strategy training (called CO-OP) to help people who had a stroke improve their ability to do everyday activities like dressing or cooking. 72 adults who had a stroke within the last 9 months took part. The training focused on using problem-sol…

This study looked at whether giving a single dose of pregabalin before kidney stone surgery could lower pain and reduce the need for opioid painkillers afterward. About 118 adults having ureteroscopy with a ureteral stent were randomly given either pregabalin or a placebo. The ma…

This study looked at how lowering phenylalanine levels with the drug Palynziq affects the brain and thinking skills in adults with PKU. Six participants had brain scans and cognitive tests before and after treatment. The goal was to understand changes in brain structure, chemistr…

This study looked at how a night of restricted sleep changes blood flow to the brain in healthy adults. Researchers compared 16 men and women to see if the effect is stronger in males. Participants had their brain blood flow measured after normal sleep and after limited sleep. Th…