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New hope for COVID brain fog: simple strategy training shows promise

NCT ID NCT06136871

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 34 times

Summary

This study tested a remote cognitive strategy training called CO-OP for people with post-COVID syndrome who have trouble with everyday tasks due to brain fog. 65 participants learned a goal-plan-do-check method to improve their daily functioning. The study focused on whether this approach is feasible and acceptable, and also measured its effect on activity performance and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Missouri Department of Occupational Therapy

    Columbia, Missouri, 65211, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cognitive strategy training (CO-OP)

What this could lead to

If successful, this approach could offer a practical way to help people with post-COVID cognitive issues manage everyday tasks better.

What could go wrong

This is a small feasibility study, not a large trial. The results may not apply to everyone, and the training may not work for all types of cognitive problems.

Conditions

The condition(s) this trial relates to.

COVID-19 long COVID-19 post-COVID-19 disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.