University Of Iowa
Clinical trials sponsored by University Of Iowa, explained in plain language.
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Rural Seniors' fall risk cut by smarter meds plan
Prevention CompletedThis study tested a medication care plan to reduce falls in 398 rural adults aged 60 and older. Participants got a personalized plan to safely stop or reduce medications that increase fall risk. Researchers tracked falls and injuries over time to see if the plan helped prevent ac…
Phase: NA • Sponsor: University of Iowa • Aim: Prevention
Last updated May 20, 2026 11:54 UTC
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New gel under dentures could ease dry mouth and improve fit
Symptom relief CompletedThis study tested two dissolvable gels (MI Paste and Biotene Dry Mouth Gel) placed under removable dentures to see if they improve comfort, retention, and dry mouth symptoms. 67 adults with partial or full dentures took part. The goal was to find simple, non-sticky options beyond…
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated May 26, 2026 03:03 UTC
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Veterans' knee surgery pain eased by talking therapy, study finds
Symptom relief CompletedThis study tested whether a brief behavioral program called Acceptance and Commitment Therapy (ACT) could help at-risk veterans avoid persistent pain and disability after total knee replacement. About 400 veterans scheduled for knee surgery were randomly assigned to receive eithe…
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Can a special brace stop arthritis after an ankle break?
Knowledge-focused CompletedThis study tested if custom carbon fiber braces can reduce harmful forces on the ankle joint after a fracture. 22 adults with healed ankle fractures walked with different brace designs to measure joint stress and pain. The goal is to help doctors design braces that lower the chan…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:28 UTC
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Habit hack for meds: simple worksheet may boost adherence
Knowledge-focused CompletedThis study tested whether a habit-building worksheet and a chat with a pharmacist could help people remember to take their new long-term medications for heart disease or depression. Thirty-three adults took part. Researchers measured how well the habit worksheet worked compared t…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:28 UTC
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Smart sensor vs. finger prick: which catches low blood sugar better after birth?
Knowledge-focused CompletedThis study looked at whether using a continuous glucose monitor (CGM) in the hospital right after childbirth can better detect low blood sugar (hypoglycemia) in women with type 1 or type 2 diabetes, compared to the usual finger-prick tests. 39 women in their third trimester who o…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:28 UTC
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Ankle brace design under the microscope: small study, big data
Knowledge-focused CompletedThis study looked at how different carbon fiber brace designs change the forces on the ankle joint. Nine healthy adults wore custom braces while walking, and researchers used a computer model to estimate joint stress. The goal was to improve the model and procedures for future br…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:25 UTC
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Dental researchers track socket healing after grafting with Bio-Oss collagen®
Knowledge-focused CompletedThis study followed 39 adults who needed a tooth pulled and replaced with a dental implant. After extraction, the empty socket was filled with Bio-Oss Collagen®, a bone graft material. Researchers then checked healing at different times (3, 6, or 9 months) using scans and bone sa…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:25 UTC
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Survey reveals hidden psychological factors behind vaccine choices
Knowledge-focused CompletedThis study surveyed 1,786 US adults to identify psychological traits—like trust, fear of needles, and openness—that are linked to how people feel about vaccines and whether they get them. The goal was to find new ways to encourage vaccination, especially in older adults. No treat…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:25 UTC
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New scale could help track nerve disease in kids
Knowledge-focused CompletedThis study aimed to create and test a new scale to measure symptoms and physical abilities in children with Charcot-Marie-Tooth (CMT) disease, a nerve condition that affects movement and sensation. Researchers enrolled 500 children under 21 with CMT at multiple centers. They asse…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:15 UTC
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Can remote physical therapy match in-person care after shoulder replacement?
Knowledge-focused CompletedThis study looked at whether doing physical therapy at home through video calls works as well as going to a clinic after shoulder replacement surgery. About 93 people who had shoulder replacement took part. Researchers measured how well they could move their shoulder, their pain …
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Leg brace cuff design may change how you walk and feel
Knowledge-focused CompletedThis study tested 35 adults with ankle arthritis or lower limb injury to see how different cuff designs on carbon fiber leg braces affect comfort, walking mechanics, and user preference. Participants walked with several cuff styles while researchers measured foot pressure, pain, …
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Texting your symptoms: 214 patients help map COVID-19's daily patterns
Knowledge-focused CompletedThis study enrolled 214 people who tested positive for COVID-19. Participants received daily text messages asking about their symptoms, such as fever, cough, and loss of taste or smell. The goal was to learn how symptoms develop and change throughout the infection, not to test an…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 19, 2026 11:46 UTC