University Hospital Heidelberg

This study looks at people with a severe type of stroke where bleeding enters the brain's fluid spaces, often requiring a drain. Researchers want to see if adding an extra drain in the lower back, along with the standard head drain, helps patients recover better and avoids the ne…

This study tests a precise type of radiation called proton beam therapy for women whose breast cancer has returned after earlier radiation and a second lumpectomy. The goal is to control the cancer while reducing severe skin side effects. Twenty participants will receive 15 daily…

This study compares lying on your back for 1 day versus 5 days after a specific type of corneal transplant (DMEK) for Fuchs dystrophy. Researchers want to see if a longer period of lying flat helps the transplant stay attached and reduces the need for extra procedures. About 102 …

This study looks at whether taking probiotics (with or without vitamin B12) can improve the results of standard gum disease treatment. About 60 adults with advanced gum disease will receive either standard care alone or standard care plus probiotics for 3 months. Researchers will…

This study tests a precise type of radiation called carbon ion therapy for people whose head-and-neck cancer has returned after standard treatment. About 72 adults who cannot have surgery will receive this therapy to see if it causes fewer severe side effects and helps control th…

This study tests a shorter, more intense radiation treatment (proton or carbon ion) given before surgery for soft tissue sarcoma of the arms or legs. The goal is to see if this approach reduces wound healing problems and improves quality of life compared to standard 5-week radiat…

This study tests whether advanced PET/CT scans can more accurately show the edges of esophageal cancer before and after chemotherapy. By comparing scan results with tissue removed during surgery, researchers hope to improve surgical planning. The study enrolls 30 adults with earl…

This study looks at two types of radiation after prostate removal: standard photon therapy and newer proton therapy. The goal is to see if protons cause fewer bowel problems and improve quality of life. About 900 men who have had prostate surgery will take part. The study also ch…

This study tests whether proton beam radiation causes fewer side effects than standard photon radiation in people with glioblastoma, a serious brain cancer. About 326 adults who need radiation after surgery or biopsy will be randomly assigned to one of the two types. The main goa…

This study looks at two types of radiation for people with 4 to 15 brain tumors that have spread from other cancers. One is CyberKnife, which delivers precise radiation in 1 or 2 sessions, and the other is whole-brain radiotherapy, which takes 10 sessions. The goal is to see whic…

This study tests whether giving a single dose of radiation directly to the tumor site during breast-conserving surgery can reduce fatigue compared to the standard 3-6 weeks of whole-breast radiation. The trial enrolls 202 women aged 50 or older with low-risk, early-stage breast c…

This study tests whether a special MRI scan can detect and track different types of interstitial lung disease (ILD) better than standard CT scans. About 200 adults with ILD will get MRI scans over time to see if the images can show which lung changes are reversible or getting wor…

This study is looking at whether a blood test can help doctors monitor meningioma brain tumors after radiation treatment. Researchers will measure tiny particles called extracellular vesicles in the blood of 60 patients before and after radiotherapy. The goal is to find a safer w…