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New radiation approach aims to speed sarcoma recovery

NCT ID NCT04946357

First seen Mar 10, 2026 · Last updated Jun 23, 2026 · Updated 15 times

Summary

This phase 2 trial tests a shorter course of proton or carbon ion radiation (2-3 weeks instead of 5) given before surgery for extremity soft tissue sarcoma. The main goal is to see if this approach reduces wound healing problems after tumor removal. The study enrolls 42 adults with resectable sarcoma and no distant spread.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital Heidelberg, Department of RadioOncology

    RECRUITING

    Heidelberg, Baden-Wurttemberg, 69120, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

proton or carbon ion radiation

What this could lead to

If successful, this shorter radiation schedule could become a new standard before sarcoma surgery, reducing side effects and improving quality of life.

What could go wrong

This is a small early-phase trial with only 42 participants, so results may not apply broadly. The main risk is wound healing problems after surgery, which the study is specifically measuring.

Conditions

The condition(s) this trial relates to.

sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.