Shorter radiation before sarcoma surgery: could it reduce wound problems?

NCT ID NCT04946357

Ongoing Disease control Sponsor: University Hospital Heidelberg Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This phase 2 trial tests whether a shorter course (2-3 weeks) of proton or carbon ion radiation before surgery for extremity soft tissue sarcoma is safe and feasible. The main goal is to see if it reduces wound healing problems after surgery. The study enrolls 42 adults with resectable sarcoma and compares two types of particle radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: proton or carbon ion radiation
What this could lead to: If successful, this could offer a shorter, more convenient radiation schedule before sarcoma surgery with fewer side effects and better wound healing.
What could go wrong: This is a small early-phase trial (42 participants) testing safety and feasibility, not yet proven to be better than standard treatment. The results may not apply to all sarcoma patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOFT TISSUE SARCOMA

Contacts and locations

Locations

University Hospital Heidelberg, Department of RadioOncology

Heidelberg, Baden-Wurttemberg, 69120, Germany

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