University College, London

This study looks at whether adding a special type of radiation (SABR) to usual cancer therapy can help people with non-small cell lung cancer that has spread to only a few spots in the body. About 140 adults will be randomly assigned to get either standard treatment alone or stan…

This early-phase trial tests a personalized treatment where a patient's own immune cells are modified to attack cancer cells in certain blood cancers, including acute lymphoblastic leukemia, lymphoma, and chronic lymphocytic leukemia. The study includes 72 adults and focuses on s…

This study looks at whether low risk thyroid cancer patients need radio-iodine treatment after having their thyroid removed. About 504 participants will be followed to see if skipping this treatment affects cancer recurrence or survival. The goal is to find out if some patients c…

This early-phase trial tests a new treatment called GD2 CAR T cells in 12 children and teens (ages 1-16) with neuroblastoma that has come back or not responded to standard therapy. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recog…

This study tests whether giving the antibiotic ciprofloxacin daily can prevent bacterial infections in children (ages 1-17) being treated for acute lymphoblastic leukemia. About 313 children in the UK will either receive ciprofloxacin or standard care during the first month of ch…

This study tests whether advanced MRI scans can tell the difference between aggressive and harmless kidney tumors before surgery. Currently, standard scans show tumor size but not type, and biopsies are invasive. Researchers will compare MRI results with tissue removed during sur…

This study tests a new surgical technique called NeuroSAFE during robotic prostate removal for prostate cancer. The goal is to see if it helps men keep erectile function and urinary control better than standard surgery. About 407 men who are potent and continent before surgery wi…

This study tests whether a school-based social prescribing program can reduce loneliness in teenagers. About 215 students who feel lonely will be randomly assigned to either get connected with a link worker who helps them find community activities, or just receive information abo…

This study looks at how much stress surgeons feel during hip and knee replacement surgeries, comparing traditional methods with robot-assisted ones. Six experienced orthopedic surgeons will wear a brain-monitoring headband and heart rate monitors while they operate. The goal is t…

This study looks at whether people with memory problems will wear digital devices like smartwatches and sleep headbands, and use smartphone apps, to collect health data. Researchers will combine this data with medical records to build computer models that might one day predict de…

This study looks at whether a blood test can help doctors choose the most effective treatment for men with metastatic prostate cancer. Researchers will analyze blood samples from 192 patients during their standard care to track cancer-related markers. The goal is not to test a ne…

This study follows 814 people with early-stage non-small cell lung cancer to understand how the cancer changes and spreads over time. By analyzing tumor samples and patient data, researchers aim to find patterns that predict recurrence and improve survival. No new treatment is te…

This study looks at the genetic makeup of lung cancers that were found through low-dose CT scans. Researchers want to understand why some of these cancers grow quickly while others grow slowly. About 526 people who had surgery to remove their lung cancer are taking part. The goal…