Universitaire Ziekenhuizen Ku Leuven

This study is testing a custom-made metal implant designed to resurface small areas of damaged knee cartilage. It is for people whose previous cartilage repair treatments have failed and who are not yet candidates for a full knee replacement. The goal is to see if this personaliz…

This study compares three different designs of total knee replacement implants to see which one helps patients regain better function and feel more like a natural knee. It involves 75 people with severe knee arthritis who need a knee replacement. Researchers will measure pain, mo…

This study looks back at medical records to understand how common and severe side effects are after patients receive a single morphine injection into the spine for surgery pain. Researchers will review data from 600 adults who had this procedure to learn more about risks like bre…

This study aims to understand how getting an implantable cardioverter-defibrillator (ICD) affects a person's quality of life over time. Researchers will follow 400 patients who have the device to track changes in their physical and emotional health, acceptance of the device, and …

This study aims to understand if general anesthesia given to pregnant women during abdominal surgery affects their child's intelligence and development later in life. Researchers will compare three groups of children: those exposed to anesthesia before birth, those not exposed, a…

This study aims to better understand why some critically ill patients with liver cirrhosis develop a severe, life-threatening fungal lung infection called invasive pulmonary aspergillosis (IPA). Researchers will analyze data and tissue samples from 450 adult patients admitted to …

This study aims to better understand the real-life experiences of people living with an implantable cardioverter-defibrillator (ICD) and their partners or caregivers. Researchers will conduct in-depth interviews with 250 participants to explore how the device affects education, p…

This study aims to understand what makes spinal deformity surgery care more valuable by linking patient outcomes to treatment costs. Researchers will follow 140 adult patients who had spinal surgery at a specific Belgian hospital, tracking their recovery and costs over two years.…

This study aims to find out if a drug called sugammadex, used to reverse muscle relaxants after surgery, can cross the human placenta and reach a developing fetus. Researchers will use donated placentas from healthy pregnancies in a lab model to measure drug transfer. The goal is…

This study is a survey asking Belgian spine surgeons about their current practices for advising patients when to return to work after lower back surgery for nerve pain. It aims to understand what advice surgeons give, what makes giving good advice difficult or easier, and how the…

This study aims to understand what helps working-age people return to their jobs after knee replacement surgery. Researchers will follow 88 patients under age 63 for 1.5 years, tracking their recovery, pain medication use, and ability to work and play sports. The goal is to ident…