Umc Utrecht

This study looks at whether women with high-risk pregnancies can safely monitor their baby's heart rate and their blood pressure from home instead of going to the hospital. About 450 pregnant women in four European hospitals will use certified home devices, with healthcare profes…

This study tests whether adding zanubrutinib to standard rituximab therapy can improve walking and arm function in people with a rare blood condition (IgM MGUS) that causes nerve damage. About 35 adults will receive the combination for up to a year, with follow-up lasting 3 years…

This study looks at whether a 9-month structured and personalized exercise program can reduce cancer-related physical fatigue and improve quality of life in 357 people with stage IV (metastatic) breast cancer. Participants will follow an exercise plan tailored to their abilities …

This study tests whether focused ultrasound (MR-HIFU), alone or with standard radiation, can better relieve bone pain caused by cancer that has spread. About 216 adults with painful bone lesions will be randomly assigned to one of three groups. The goal is to see if adding ultras…

This study tests a small mesh device, called the coronary sinus reducer, in 50 people with chest pain caused by tiny heart vessel disease. The device is placed in a heart vein to increase pressure and improve blood flow. Researchers will measure changes in blood flow and daily ch…