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New drug cocktail aims to reverse nerve damage in rare blood disorder

NCT ID NCT05939037

First seen May 16, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This study tests whether adding zanubrutinib to standard rituximab therapy can improve walking and arm function in people with a rare blood condition (IgM MGUS) that causes nerve damage. About 35 adults will receive the combination for up to a year, with follow-up lasting 3 years. The goal is to see if the treatment reduces disability and is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Medical Center Utrecht

    Utrecht, Utrecht, 3584CX, Netherlands

Conditions

Explore the condition pages connected to this study.