New hope for rare nerve disorder: drug combo trial targets mobility

NCT ID NCT05939037

First seen May 16, 2026 ยท Last updated May 16, 2026

Summary

This study tests whether adding zanubrutinib to standard rituximab therapy can improve walking and arm function in people with nerve damage from a blood condition called IgM MGUS. About 35 adults will receive the combination for up to 12 months, with follow-up over 3 years. The goal is to see if the treatment helps reduce disability and is safe.

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Contacts and locations

Locations

  • University Medical Center Utrecht

    Utrecht, Utrecht, 3584CX, Netherlands

Conditions

Explore the condition pages connected to this study.