Umc Utrecht

This study tested a new ceramic putty against the standard bone graft surgery for repairing the gum gap (alveolar cleft) in 84 children with unilateral cleft lip and palate. The goal was to see if the putty could rebuild bone just as well, with less pain. Results will show how mu…

This study tested whether using a stem cell transplant early in the disease is better than starting with standard immunosuppressive drugs for people with a severe form of scleroderma. Sixty adults with early diffuse scleroderma were randomly assigned to either receive their own s…

This study tested a two-step surgical approach for 22 people with esophageal cancer who had hardened arteries, which raises the risk of a dangerous leak after standard surgery. About two weeks before the main tumor-removal surgery, patients had a key blood vessel temporarily bloc…

This study tested a fully automated system that delivers both insulin and glucagon to manage blood sugar in adults with type 1 diabetes. Over 12 months, 243 participants used either this dual-hormone system or standard care. The goal was to see if the new system helps people spen…

This study compared two surgical methods for stomach cancer: laparoscopic (keyhole) surgery and open surgery. The goal was to see if keyhole surgery leads to a shorter hospital stay and fewer complications. 210 adults with resectable stomach cancer took part. Results will help do…

This study tested a new brain implant that helps people with locked-in syndrome communicate. The implant records brain signals from the surface of the brain and sends them wirelessly to a device that can spell words or control the environment. Six participants tried the system at…

This completed study tested whether a non-invasive MRI technique (31P-MRS) can monitor changes in energy production in the heart and calf muscles of cancer patients receiving chemotherapy with anthracyclines or platinum drugs. Twelve adult cancer patients underwent three imaging …