The University Of Hong Kong

This study is testing whether chewing xylitol gum for 4 weeks can help daily smokers reduce or quit smoking. Researchers will compare 134 smokers who receive the gum plus text message reminders to those who only get basic quitting advice. The main goal is to see if using the gum …

This study will test if taking a daily folic acid (vitamin B9) pill for 90 days helps adults survive longer and recover better from sudden kidney failure caused by infections like sepsis. Researchers will compare about 382 patients who receive folic acid plus standard hospital ca…

This study is testing a combination treatment for people whose nasopharyngeal cancer has come back in the original area. Participants will receive a drug (pembrolizumab) and chemotherapy before surgery to remove the tumor, followed by more of the drug after surgery. The goal is t…

This is a small, early-stage study to see if taking a specific probiotic supplement for 10 weeks can help lower high blood pressure. Researchers will enroll 30 middle-aged Chinese adults with untreated hypertension to test if the probiotic affects their blood pressure, gut bacter…

This study tests whether special nurse-led education before hospital discharge helps patients better manage chronic conditions like heart disease and diabetes at home. Researchers will compare 120 hospitalized adults who receive this education to those who get usual care. The mai…

This study is testing if high-dose Vitamin D can help the brain clear blood clots faster after a severe type of stroke called an intracerebral hemorrhage. Researchers will give 40 participants either Vitamin D pills or standard care to see if the vitamin is safe and helps shrink …

This study is testing if using a weight loss medication (semaglutide) before total knee replacement surgery can lead to better outcomes for patients who are obese. It will involve 54 people with knee arthritis who are scheduled for surgery. The main goal is to see if this approac…

This study is testing whether a team approach led by nurses and allergy specialists can safely and effectively remove penicillin allergy labels from patients' medical records. It will compare this new method to the traditional doctor-only approach to see if it works just as well,…

This study tests whether adding a new drug called asciminib to standard maintenance therapy can better prevent leukemia from returning after a stem cell transplant. Researchers will compare two groups: one receiving the standard drug alone and another receiving the standard drug …

This study is testing if a drug called dapagliflozin can help people who have had a Fontan heart surgery. It aims to see if the drug improves their ability to exercise and their heart function over three months. The trial will involve about 30 adolescents and adults in Hong Kong …

This study is testing a new risk calculator designed to make cancer treatment safer for people aged 65 and older. It will guide doctors on whether to start with a lower, gentler dose of medication for patients at high risk of severe side effects. The goal is to reduce dangerous r…

This study is testing if adding a new eye drop called Diquafosol to standard treatment helps people with severe spring eye allergies. It will involve 94 participants, aged 6 and up, who have active, moderate-to-severe symptoms. The goal is to see if the combination better control…

This study is testing a new system to help cancer survivors manage their weight through exercise. Doctors will use a simple 3-step plan (assess, advise, refer) to connect eligible patients with a weight management program. The goal is to see if this structured approach gets more …

This study aims to find out if very small chest tubes can be used to treat fluid buildup in the chest caused by cancer (malignant pleural effusion). Researchers will compare three different small tube sizes (8, 12, and 14 French) in 60 patients to see which works best for a proce…

This study is testing a personalized digital program designed to help older adults living at home who are at risk of losing muscle strength (sarcopenia) and becoming frail. The program provides tailored exercise and nutrition plans through a digital platform, aiming to improve st…

This study is testing a 12-week health coaching program delivered via the WeChat app. It aims to see if personalized support can help adults with multiple conditions like high blood pressure, diabetes, or heart disease improve their lifestyle habits, symptoms, and overall well-be…

This study is testing a new program to help women in Hong Kong reduce their alcohol use. It combines brief counseling, daily check-ins via a phone app, and a private social media support group. Researchers will compare this approach to standard health education to see if it's hel…

This study is testing whether a simple, at-home urine test can be used to screen for cervical cancer. Researchers will recruit 8,620 women to see if women find the urine test acceptable and if it can accurately identify those who need a follow-up exam. The goal is to make screeni…

This study is testing a smartphone app that records heart sounds to see if it can accurately detect murmurs linked to congenital heart disease. Researchers will record the heart sounds of 220 participants during their normal hospital visits to build a database for training future…

This study aims to find out if regular low-dose CT scans can help detect lung cancer early in people at high risk due to smoking. It will enroll 15,000 current or former heavy smokers in Hong Kong, randomly assigning half to receive scans and half to receive usual care, and follo…

This study is testing a new, personalized counseling program designed to help young adults in Hong Kong who have recently quit smoking avoid starting again. The program tailors support based on the individual's specific challenges and motivations. Researchers will enroll 100 youn…

This study aims to see if comic books are a more effective tool than standard information sheets for teaching primary school students about the dangers of smoking and vaping. Researchers will enroll about 1,000 students in Hong Kong, giving one group comics and another group trad…

This study is testing whether a non-invasive brain stimulation technique, combined with movement training, can reduce movement problems and improve coordination in children with cerebellar ataxia. Researchers will compare children who receive the brain stimulation plus training t…

This study is testing a hidden smartphone app on WeChat designed to safely support Chinese immigrant women in Hong Kong who are experiencing intimate partner violence. The app is disguised as a general health program to protect users' privacy. Researchers want to see if the app i…

This study aims to see if a simple, self-administered acupressure technique can help reduce persistent cough and related symptoms like shortness of breath and fatigue in people who have had lung cancer. 80 participants will either practice acupressure for 8 weeks or receive an ed…

This study is testing whether an AI-powered smartphone app can help people with knee osteoarthritis manage their pain as effectively as seeing a physiotherapist in person. Researchers will compare three groups: one using only the app, one having only in-person sessions, and one u…

This study is testing whether a specific type of acupuncture can help teenagers who are feeling stressed, anxious, or depressed, and having trouble sleeping. Researchers will compare this special acupuncture treatment to a standard acupuncture method over 8 weeks. They will also …

This study is testing whether a brief group therapy program for insomnia, led by trained non-professionals instead of clinicians, can help improve sleep quality for older adults in Hong Kong. Researchers will compare 50 participants who either attend the group sessions or receive…

This study is testing a new communication training program called 'ReFrame-R' designed to help older adults in Hong Kong improve their relationships with their adult children. The program teaches skills for clearer communication and healthier family roles, with the goal of improv…

This small pilot study aims to see if an 8-week group mindfulness program can help parents caring for children with autism or ADHD. It will check if the program reduces their stress, anxiety, depression, and sleep problems. The study involves 30 participants who will attend weekl…

This study is testing whether a six-week talk therapy program for insomnia can improve sleep and reduce mental distress in young people in Hong Kong. It will involve 770 youths aged 12-24 who report moderate distress and sleep problems. Community hubs will be randomly assigned to…

This study aims to see if acupuncture can help control pain and improve recovery for people after hemorrhoid removal surgery. Researchers will compare real acupuncture treatments to a fake, look-alike procedure over the first five days after surgery. The main goal is to find out …

This study is testing a program called B-Mindful-Life that aims to help caregivers of people with neurological disorders (like Alzheimer's or Parkinson's) become more physically active and manage stress. The program combines mindfulness training with lifestyle counseling and is d…

This study is testing a new 12-week support program designed to help family members caring for someone with dementia. The program uses virtual meetings and phone calls to help caregivers find more positive meaning in their role, with the goal of reducing stress and improving thei…

This study is testing a new program to see if it helps more older adults in Hong Kong sign up for and use their local District Health Centre. The program involves home visits from trained students followed by a month of AI-generated health messages. Researchers want to know if th…

This study is testing a 10-day messaging and chatbot program called ChatACP. It aims to help family members of frail nursing home residents feel more prepared to talk about and plan for their loved one's future medical and personal care wishes. Researchers will compare the chatbo…

This study aims to understand what happens to the kidneys in patients with hepatorenal syndrome, a serious kidney complication in people with severe liver disease. Researchers will examine small pieces of kidney tissue taken during liver transplant surgery to see if the kidneys a…