Spaulding Rehabilitation Hospital

This study looks at whether short periods of breathing low oxygen, combined with spinal cord stimulation and walking practice, can help people with chronic spinal cord injury walk better. It includes 60 adults aged 18 to 80 who can already walk a little. The goal is to see if thi…

This study tests a wrist-worn sensor system called StrokeWear that reminds and encourages stroke survivors to use their weaker arm during daily activities at home. About 88 people who had a stroke 1 to 6 months ago will either use the sensor with a home exercise program or follow…

This study tests a wrist-worn sensor system called StrokeWear that reminds and encourages stroke survivors to use their weaker arm during daily activities at home. 32 adults who had a stroke 6 months to 5 years ago will either use the sensor with a home exercise program or follow…

This study tests whether a gentle nerve stimulation device, used daily at home, combined with weekly support therapy sessions, can reduce stomach-related anxiety and improve digestion in people with functional dyspepsia. About 80 adults aged 18-65 with this condition will partici…

This study tests whether breathing low oxygen, combined with spinal cord stimulation and walking practice, can improve walking for people with chronic spinal cord injury. About 60 adults with some walking ability will take part. The goal is to see if this approach helps them walk…

This study tests whether MDMA-assisted therapy can reduce pain and improve quality of life in people with fibromyalgia, a chronic pain condition. Twenty adults will receive two therapy sessions with MDMA while researchers scan their brains to see how the drug affects pain signals…

This study tests if a portable brain stimulation device, used at home along with sensory training, can reduce phantom limb pain in people with amputations. About 290 adults who experience pain at least weekly will either receive the device plus training or continue their usual ca…

This study explores whether a slow, controlled yoga breathing technique called Ujjayi can improve breathing, lung function, and sleep quality in people with spinal cord injuries. Twenty adults aged 18-60 who use wheelchairs will practice Ujjayi breathing for six weeks. Researcher…

This study tests whether shockwave therapy can reduce pain and improve knee function in athletes who developed knee osteoarthritis after ACL reconstruction. Researchers will measure pain, movement, and inflammation in 70 participants. The goal is to find a non-surgical way to eas…

This study tests whether showing stroke survivors real-time data from wearable ring sensors on their smartphone can encourage them to use their stroke-affected arm more during daily activities. About 50 chronic stroke survivors (more than 12 months since their stroke) aged 18 to …

This study tests a new drug-free approach for fibromyalgia pain. Researchers want to see if a short mental training session before acupuncture helps the patient's brain sync up with the clinician's brain, making the treatment more effective. The study will enroll 100 adults with …

This study is testing a device called SynPhNe that stroke survivors can use at home to retrain their hand and arm movement. The goal is to see if it works better than standard care alone. About 40 people who had a stroke at least 6 months ago and have moderate hand weakness will …

This study tests whether a gentle brain stimulation technique (tDCS combined with ultrasound) can reduce chronic pain in people with carpal tunnel syndrome. Researchers will compare active stimulation to a sham (fake) treatment in 95 adults aged 18–80 who have had pain for at lea…

This study looks at how placebos (inactive treatments) affect the brains of people recovering from stroke. Researchers will give placebos openly or secretly to 56 adults with chronic stroke and measure brain activity with EEG. The goal is to understand how placebos work in the br…

This study looks at how the Q-Collar, a device worn around the neck, changes the way blood flows to the brain during rest and exercise. Twenty healthy adults aged 18-30 will complete two sessions—one with the collar and one without—while doing standing tests, breathing exercises,…

This study tests whether a camera-based system can track arm movements and posture during robot-assisted therapy for stroke survivors. The goal is to see if group therapy sessions (up to 3 people) work as well as individual sessions. About 42 adults who had a stroke 6 months to 6…

This study looks at how brief periods of breathing low oxygen (intermittent hypoxia) might improve movement and walking in people with chronic spinal cord injury. Researchers will measure changes in walking endurance and leg strength in 44 adults with incomplete injuries. The goa…

This study looks at how the brains of romantic partners communicate compared to strangers. Researchers will record brain activity from two people at the same time using EEG, both in the same room and remotely. The goal is to understand what factors, like age or relationship quali…