Spaulding Rehabilitation Hospital

This study tests a 6-month exercise program for people with high-level spinal cord injury. Participants use a rowing machine that also electrically stimulates their leg muscles. Some will also receive a breathing support machine or a drug called Buspar to see if these help improv…

This study tests whether short, mild low-oxygen breathing sessions can improve walking and leg strength in people who had a spinal cord injury 2 to 12 months ago. About 125 adults aged 18 to 70 will take part. The goal is to see if this simple, non-invasive approach helps restore…

This study tests a new digital prosthetic liner combined with an exercise program to improve comfort and mobility in people who lost a leg due to type 2 diabetes. About 38 participants will use the smart liner and exercise routine, and researchers will measure pressure on the lim…

This study tests whether two types of gentle brain stimulation—tDCS and TUS—can reduce pain and improve daily function in people with chronic low back pain. About 40 adults aged 18 to 85 with persistent pain will receive either real or sham stimulation. The goal is to see if thes…

This study tests a system called GaitBetter that combines walking practice with thinking exercises to help stroke survivors improve their walking and balance. About 76 adults who had a stroke (either within 8 weeks or more than 6 months ago) will use the system. The goal is to se…

This study tests two treatments—mirror therapy and mild brain stimulation (tDCS)—to help people with phantom limb pain after a leg amputation. About 132 adults with long-term pain will try one of four combinations of real or fake treatments for 4 weeks. The goal is to see if thes…

This study tests whether a non-invasive brain stimulation technique (tDCS plus ultrasound) combined with physical therapy can improve balance problems in people with Parkinson's disease. Forty adults with Parkinson's who have balance issues will receive either real or fake stimul…

This study tests a method called conditioning open-label placebo (COLP) to help patients with spinal cord injury, multiple injuries, or burns use fewer opioids while still getting good pain relief. About 66 adults in intensive rehab will receive placebos they know are placebos, a…

This study tests whether gentle electrical and ultrasound brain stimulation can reduce pain and improve daily function in people with knee osteoarthritis. About 64 adults with chronic knee pain will receive either real or fake (sham) stimulation to see if it lowers pain scores. T…

This study looks at whether short periods of breathing low-oxygen air can help people with chronic spinal cord injury walk better. Researchers will measure leg strength, reflexes, and walking endurance in 30 participants. The goal is to find a simple, drug-free way to improve mob…