Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New combo therapy aims to quiet phantom limb pain

NCT ID NCT02487966

Symptom relief Sponsor: Spaulding Rehabilitation Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining mirror therapy with a gentle brain stimulation technique (tDCS) can reduce phantom limb pain in people with leg amputations. 132 adults with chronic pain will be assigned to different treatment groups to see which approach works best. The goal is to find a better way to manage this common and distressing condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

132 people

The number who actually took part.

Start date

Jul 2015

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Able to provide informed consent to participate in the study. 2. Subject is older than 18 years. 3. Unilateral lower limb amputation. 4. Traumatic amputation greater than 1 year ago. 5. Chronic PLP for at least 3 months previous to enrollment in the study, experienced regularly for at least once a week. 6. Average pain of at least 4 on a numeric rating scale in the previous week (NRS; ranging from 0 to 10). 7. If the subject is taking any medications, dosages must be stable for at least 2 weeks prior to the enrollment of the study. Exclusion Criteria: 1. Pregnancy or trying to become pregnant in the next 2 months. 2. History of alcohol or drug abuse within the past 6 months as self-reported. 3. Presence of the following contraindication to transcranial direct current stimulation and transcranial magnetic stimulation * Ferromagnetic metal in the head (e.g., plates or pins, bullets, shrapnel) * Implanted neck or head electronic medical devices (e.g., cochlear implants, vagus nerve stimulator) 4. History of chronic pain previous to the amputation. 5. Head injury resulting in loss of consciousness for at least 30 min or pos-traumatic amnesia for greater than 24 hours, as self-reported 6. Unstable medical conditions (e.g. uncontrolled diabetes, uncompensated cardiac issues, heart failure or chronic obstructive pulmonary disease). 7. Uncontrolled Epilepsy or prior seizures within the last 1 year. 8. Suffering from severe depression (as defined by a score of \>30 in the Beck Depression Inventory).\* 9. History of unexplained fainting spells or loss of consciousness as self-reported during the last 2 years. 10. History of neurosurgery, as self-reported. 11. Mirror Therapy in the previous 3 months

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Amputation, traumatic are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Amputation, Traumatic Phantom Limb

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Amputation, traumatic Phantom limb pain

Contacts and locations

Locations

  • IMREA HCFMUSP - Rede Lucy Montoro

    São Paulo, 04116-030, Brazil

  • Spaulding Rehabilitation Network Research Institute

    Charlestown, Massachusetts, 02129, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.