Sixth Affiliated Hospital, Sun Yat-sen University

This study looked at how well the drug upadacitinib works for Crohn's disease when it only affects the small bowel, compared to when it affects other parts of the digestive tract. Researchers reviewed records of 3 people with active Crohn's who took upadacitinib for 12 weeks. The…

This study looked at 150 adults with Crohn's disease who were treated with ustekinumab, a targeted drug. Researchers used high-tech imaging to measure inflammation deep in the gut wall and checked if that helped predict how well the drug worked over 12 months. The goal was to see…

This study looked at whether adding mesalazine (a standard anti-inflammatory drug) to biologic treatments helps more people with moderate to severe ulcerative colitis reach endoscopic remission (healing of the gut lining). 438 adults took part. The goal was to see if the combinat…

This study looked at whether placing a blood pressure monitoring catheter 1.5-2.5 cm higher on the wrist than usual reduces problems like kinking or blockage. It involved 486 adults having surgery who needed this type of monitoring. The goal was to see if the new spot gives more …

This study looked at 300 people with Crohn's disease to see if a computer analysis of CT scans could predict who would need surgery within a year of diagnosis. The goal was to create a tool that helps doctors decide on treatment earlier. The study did not test a new treatment, bu…

This study looked at 1,471 people with colon cancer to see how their tumor's DNA repair system (called mismatch repair status) relates to where cancer spreads in lymph nodes and how long patients live. Researchers compared two types: pMMR (normal repair) and dMMR (defective repai…

This study looked at 298 patients who had surgery for rectal cancer that had come back in the pelvis. Researchers wanted to find out how often the cancer returns again and what factors increase that risk. The goal is to help doctors better predict and manage outcomes for these pa…

This study looked back at the medical records of 400 newborns with necrotizing enterocolitis (NEC), a life-threatening gut disease. Researchers combined blood test results, organ function scores, and other clinical signs to see if they could better predict which babies would deve…

This study looked at 669 people with Crohn's disease to see if finding anal fistulas early with routine MRI scans, even before symptoms appear, leads to better long-term health. Researchers compared those with hidden fistulas to those with obvious symptoms to understand how the d…

This study looked at how well two newer biologic drugs, Ustekinumab and Vedolizumab, work for Crohn's disease in 50 Chinese patients. Researchers checked if the drugs helped heal the gut lining and reduce symptoms, and also looked at side effects. The goal was to find out what fa…