New study aims to spot which newborns will get worse from deadly gut disease
NCT ID NCT07207915
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked back at the medical records of 400 newborns with necrotizing enterocolitis (NEC), a serious gut disease. Researchers wanted to see if combining blood test results and organ function scores could better predict which babies would develop a hole in their bowel or die. The goal is to help doctors identify high-risk babies earlier.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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400 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
In this study, a retrospective analysis was conducted on 400 enrolled neonates with necrotizing enterocolitis (NEC), with data collected at The Sixth Affiliated Hospital, Sun Yat-sen University from January 2023 to June 2025.
- Ages
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1 day to 3 months
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * (1) Diagnosis of NEC and having undergone surgical treatment, confirmed by clinical manifestations (e.g., abdominal distension, bloody stools), radiological evidence (pneumatosis intestinalis, portal venous gas, or pneumoperitoneum), and pathological examination in accordance with established guidelines; (2) Availability of complete medical records for data extraction. Exclusion Criteria: * (1) Congenital gastrointestinal malformations (e.g., intestinal atresia, Hirschsprung's disease) or spontaneous intestinal perforation; (2) Hereditary metabolic disorders; (3) Incomplete clinical data or refusal of participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Sixth Affiliated Hospial, Sun Yat-sen University
Guangzhou, Guangdong, 510655, China
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Other studies related to the condition(s) this trial covers.
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