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Could a common pill boost biologic therapy for ulcerative colitis?

NCT ID NCT05205603

First seen May 06, 2026 · Last updated May 16, 2026 · Updated 2 times

Summary

This study looked at whether adding mesalazine (a standard anti-inflammatory drug) to biologic treatments helps more people with moderate to severe ulcerative colitis reach endoscopic remission (healing of the gut lining). 438 adults took part. The goal was to see if the combination works better than biologics alone for controlling this chronic disease.

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Contacts and locations

Locations

  • First Affiliated Hospital of Shantou University Medical College

    Shantou, Guangdong, China

  • First People's Hospital of Foshan

    Guangzhou, Guangdong, China

  • General Hospital of Tianjin Medical University

    Tianjin, Tianjin Municipality, China

  • Guangzhou Panyu Central Hospital

    Guangzhou, Guangdong, China

  • Nanhai Hospital, Southern Medical University

    Guangzhou, Guangdong, China

  • People's Hospital of Chongqing

    Chongqing, Chongqing Municipality, China

  • Shengjing Hospital

    Shenyang, Liaoning, China

  • Shunde Hospital of Southern Medical University

    Guangzhou, Guangdong, China

  • The Second Affiliated Hospital of Dalian Medical University

    Dalian, Liaoning, China

  • Zhejiang University

    Hanzhou, Zhejiang, China

  • the Sixth Affiliated Hospital of Sun Yat-Sen University

    Guangzhou, Guangdong, 501655, China

Conditions

Explore the condition pages connected to this study.