Rush University Medical Center

This study tests whether injecting a patient's own blood into the chest tube can stop prolonged air leaks after lung cancer surgery. About 60 adults who still have an air leak three days after surgery will receive the blood patch. Researchers will check if it reduces hospital sta…

This study tests a culturally tailored digital program for young Black men aged 15-24 who have been hospitalized for injuries. The program aims to reduce aggression, substance use, and improve access to healthcare. Participants will use a trauma-focused app and receive support to…

This study tests whether injecting a concentrated sample of a patient's own bone marrow into the knee right after meniscus surgery can slow down or prevent arthritis. One hundred adults with a torn meniscus will receive either the bone marrow injection or a saltwater placebo, and…

This study tests whether adding a patient's own bone marrow stem cells during ACL reconstruction helps the new ligament heal better. One hundred adults with a recent ACL tear will receive either stem cells or a sham procedure. The main goal is to see if the graft looks healthier …

This study tests whether giving menstrual cups to 408 economically vulnerable women in Kenya can reduce bacterial vaginosis and sexually transmitted infections. The cups may help women avoid harmful practices used to stay dry during periods. Researchers will track infections over…

This study looks at whether taking a common ulcerative colitis medication (5-ASA) in the morning versus the evening can better control hidden inflammation and improve gut health. About 32 adults with inactive ulcerative colitis but signs of low-level inflammation will take their …

This study compares two methods to prevent infections during first-time penile implant surgery for erectile dysfunction. One group receives the standard antibiotic rinse, the other uses Irrisept, a simpler cleaning solution. Researchers will follow 200 men for one year after surg…

This study tested a new way to give radiation for prostate cancer using advanced MRI scans to guide the treatment. 54 men with localized prostate cancer received either 5 sessions of radiation to the whole prostate or a longer course with a targeted boost to visible tumors. The g…

This study tests whether following the MIND diet for 2 to 3 years can slow cognitive decline and reduce dementia risk in people aged 55 and older who have had an ischemic stroke. The MIND diet combines elements of the Mediterranean and DASH diets, with extra emphasis on leafy gre…

This study tests a program where Black mothers and their 9th- or 10th-grade daughters work together to increase physical activity and improve diet, aiming to prevent obesity. About 120 pairs will join, with daughters at higher risk due to weight. The program uses activity tracker…

This study tests a new way to help people with depression by encouraging them to join fun, community-based activities like social groups or recreation. It focuses on people from underserved neighborhoods who also have weight or inactivity issues. The goal is to see if this approa…

This study tests a 12-week program called PERSEVERE for 502 family caregivers of people with Lewy body dementia (LBD). Caregivers are matched with a trained peer mentor who guides them through lessons on LBD and provides support. The goal is to see if this reduces caregiver strai…

This study compares a one-week virtual talk therapy (Cognitive Processing Therapy) to a five-day relaxation training for reducing PTSD symptoms. About 140 adults with PTSD will participate to see which approach works better and how. The goal is to find faster, more effective ways…

This study tests whether taking probiotics can reduce symptoms and improve quality of life for people with Long COVID. Researchers will track changes in symptom severity and overall well-being in 180 adults. The goal is to find a simple, safe way to help those still struggling af…

This study compares two types of hip replacement implants to see if one design leads to higher levels of metals like cobalt and chromium in the blood. Researchers will follow 52 adults receiving either a standard or a 'dual mobility' implant. The goal is to understand which impla…

This study follows 22 adults who have spine surgery (LLIF or ALIF) to see how long hip and leg weakness lasts. Participants will have their hip and knee strength measured before surgery and again at 6 weeks, 12 weeks, and 6 months after. The goal is to learn the exact timing of w…

This study looks at ways to get patients to complete follow-up surveys after shoulder surgery. About 400 adults having shoulder arthroscopy will either receive education about the importance of surveys or get Amazon gift cards for completing them. The goal is to see which method …

This study looks at how Western habits—like drinking alcohol and eating late—might raise the risk of colorectal cancer. Twelve adults who have had colon polyps in the past will try four different weekly routines, including eating at normal times or late, with or without alcohol. …

This study aims to find out if extra digestive juices from the new pancreas cause weight gain after a pancreas transplant. Researchers will measure a digestive enzyme in the stool of 50 transplant recipients and see if it relates to how much weight they gain. The goal is to bette…

This study looks at whether people can drive safely right after minor surgery with newer, short-acting anesthesia drugs. About 625 adults who have minor procedures (like hand or foot surgery) will take a driving simulator test before leaving the clinic. The goal is to see if cert…