Rush University Medical Center
Clinical trials sponsored by Rush University Medical Center, explained in plain language.
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New digital program aims to curb violence and substance use in black youth
Disease control OngoingThis study is testing a culturally tailored digital program called BrotherlyACT for young Black males aged 15-24 who have been hospitalized for injuries. The program aims to reduce aggression, substance use, and improve access to healthcare. Researchers will enroll 300 participan…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated May 01, 2026 15:59 UTC
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When you take your UC pill could change how well it works
Disease control OngoingThis study looks at whether taking a common ulcerative colitis medication (5-ASA) in the morning versus the evening affects gut inflammation and medicine levels. About 32 adults with inactive UC but signs of low-level inflammation will take the pill at different times for one mon…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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Blood patch may seal lung leaks faster after cancer surgery
Disease control ENROLLING_BY_INVITATIONThis study tests whether injecting a patient's own blood into the chest can stop air leaks after lung cancer surgery. About 60 adults who still have an air leak three days after surgery will receive the blood patch. The goal is to see if it reduces the number of days the leak las…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Stem cell boost for torn ACLs: a game changer?
Disease control ENROLLING_BY_INVITATIONThis study tests whether adding a patient's own bone marrow stem cells during ACL surgery helps the new ligament heal and integrate better. About 100 adults with a recent ACL tear will be randomly assigned to receive either standard surgery or surgery plus stem cells. The main go…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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Can a simple cup cut STIs? new trial hopes so
Disease control OngoingThis study tests whether giving menstrual cups to poor women in Kenya who trade sex for money can lower their risk of bacterial vaginosis and sexually transmitted infections. The cup may help by replacing unhygienic period materials and reducing harmful practices. About 408 women…
Phase: PHASE2 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC
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Can a buddy system ease the burden of lewy body dementia caregiving?
Symptom relief OngoingThis study tests a 12-week program where trained peer mentors (past or current caregivers) coach current caregivers of people with Lewy body dementia. The goal is to see if this support reduces caregiver strain, improves their knowledge and attitudes, and boosts the quality of li…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated May 01, 2026 15:59 UTC
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Gut health hope: probiotics tested as long COVID remedy
Symptom relief OngoingThis study tests whether taking probiotics can reduce symptoms and improve quality of life for adults with Long COVID. About 180 participants will take probiotics or a placebo daily. The goal is to see if more people move from moderate-to-severe to mild Long COVID symptoms.
Phase: PHASE2 • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated May 01, 2026 15:59 UTC
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One-Week online therapy shows promise for PTSD relief
Symptom relief OngoingThis study compares a one-week virtual therapy called Cognitive Processing Therapy (CPT) to a five-day relaxation training program to see which better reduces PTSD symptoms. About 140 adults with PTSD will take part. The goal is to find out how these treatments work and who benef…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Apr 29, 2026 15:05 UTC
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Spine surgery recovery mystery: when does hip strength return?
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 22 adults who have spine surgery (LLIF or ALIF) to see how long hip and leg weakness lasts. Researchers measure muscle strength before surgery and again at 6 weeks, 12 weeks, and 6 months after. The goal is to find out exactly when strength comes back, which is…
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 17:42 UTC
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Pancreas transplant weight gain mystery: is extra digestive juice to blame?
Knowledge-focused TerminatedThis study aims to find out if too many digestive enzymes from the new pancreas cause weight gain after transplant. Researchers will measure a specific enzyme in stool and see if it relates to weight changes. The study includes 50 adults who have received a pancreas transplant. R…
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Late-Night snacks and booze could raise colon cancer risk, study suggests
Knowledge-focused OngoingThis study looks at how Western habits like drinking moderate alcohol and eating late at night might increase the risk of colorectal cancer. Twelve adults who have had colon polyps in the past will try four different weekly routines, including eating at normal times or late, with…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Flu jab into tumors? canceled study sought to turn vaccine into cancer weapon
Knowledge-focused TerminatedThis study was designed to see if injecting the seasonal flu vaccine directly into breast cancer tumors is safe and could help the body fight the cancer. It was planned for women with triple-negative or HER2+ breast cancer who were about to start chemotherapy. The study was withd…
Phase: PHASE1 • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Hip implant showdown: does a new design raise metal levels?
Knowledge-focused OngoingThis study looks at whether a newer type of hip replacement implant (modular dual mobility) leads to higher levels of metals like cobalt and chromium in the blood compared to a standard implant. About 52 adults getting a first-time hip replacement will be randomly assigned to one…
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
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Cash or conversation? study tests best way to get patient feedback after shoulder surgery
Knowledge-focused OngoingThis study looks at ways to encourage patients to fill out health surveys after shoulder surgery. Researchers will compare two approaches: teaching patients about the importance of surveys, or offering Amazon gift cards for completing them. About 400 adults having shoulder arthro…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC