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Knee surgery patients get bone marrow shot to halt arthritis

NCT ID NCT02582489

First seen Apr 26, 2026 · Last updated Jun 21, 2026 · Updated 6 times

Summary

This study tests whether injecting a concentrated sample of a patient's own bone marrow into the knee right after meniscus surgery can slow down or prevent arthritis. One hundred adults with a torn meniscus will receive either the bone marrow injection or a saltwater placebo, and their knee function, pain, and imaging results will be tracked for a year. The goal is to see if this simple procedure can improve long-term outcomes after a common knee operation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bone marrow aspirate concentrate (BMAC)

What this could lead to

If it works, this could point toward a way to slow or prevent osteoarthritis after knee surgery, potentially reducing pain and improving long-term knee function.

What could go wrong

This is a small, early-phase trial with only 100 participants. The treatment may not provide any benefit over a placebo, and the effects on osteoarthritis progression are uncertain.

Conditions

The condition(s) this trial relates to.

osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.