Knee surgery patients get bone marrow shot to halt arthritis

NCT ID NCT02582489

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether injecting a concentrated sample of a patient's own bone marrow into the knee right after meniscus surgery can slow down or prevent arthritis. One hundred adults with a torn meniscus will receive either the bone marrow injection or a saltwater placebo, and their knee function, pain, and imaging results will be tracked for a year. The goal is to see if this simple procedure can improve long-term outcomes after a common knee operation.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Bone marrow aspirate concentrate (BMAC)
What this could lead to
If it works, this could point toward a way to slow or prevent osteoarthritis after knee surgery, potentially reducing pain and improving long-term knee function.
What could go wrong
This is a small, early-phase trial with only 100 participants. The treatment may not provide any benefit over a placebo, and the effects on osteoarthritis progression are uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States