Rush University Medical Center

This study tests whether a church-based program can help African Americans with uncontrolled high blood pressure lower their numbers. About 312 participants from churches will receive support to improve medication use and diet over 12 months. The goal is to see if this community …

This study looks at whether using noninvasive breathing support right after removing the breathing tube can help severely obese patients avoid needing the tube again. About 20% of these patients currently need to be re-intubated, which raises risks like pneumonia and longer hospi…

This study looks at two treatments for people under 60 who faint repeatedly because their heart rate drops too low. One treatment uses a catheter to zap tiny nerve clusters in the heart (cardioneuroablation), and the other uses a permanent pacemaker. The goal is to see which appr…

This study compares a team-based program that addresses both medical and social needs to standard care for managing high blood pressure. It will enroll 200 African American and Latinx adults with uncontrolled hypertension. The main goal is to see if more people can lower their sy…

This study looks at whether giving multiple doses of tranexamic acid (TXA) by mouth or through a vein can reduce blood loss and the need for blood transfusions after spine surgery. It involves 604 adults at high risk for bleeding who are having open back surgery. The goal is to f…

This study tests a pharmacist-led program to help adults with uncontrolled high blood pressure in underserved Chicago communities. Over 3 months, a mobile team provides blood pressure checks, medication management, and health education. The goal is to lower blood pressure and imp…

This study tests whether a nerve block called an erector spinae plane block (ESPB) can quickly reduce low back pain in the emergency department. About 62 adults with back pain for less than 6 weeks will receive either the ESPB or a placebo injection. Researchers will track pain l…

This study tests a program called NurseNET, where trained nurses provide a short-term PTSD treatment called Narrative Exposure Therapy in primary care. About 100 adults with PTSD symptoms will receive 4 to 6 sessions to help process difficult memories. The goal is to see if nurse…

This study tests a telehealth therapy for children aged 2-12 with genetic conditions like Fragile X or Angelman syndrome who have intellectual disabilities and challenging behaviors. Over 3-6 months, parents work with a therapist via video calls to learn strategies that promote p…

This study tests whether morning bright light therapy can improve gut health and quality of life in people with Crohn's disease or ulcerative colitis. Researchers will measure changes in intestinal barrier function, inflammation, and gut bacteria. The study enrolls 30 adults with…

This study compares a new knee brace called KRONOS with the standard Breg T-Scope brace after ACL reconstruction surgery. The goal is to see if KRONOS reduces pain and helps people recover faster. About 40 adults having their first ACL surgery will take part.

This study tests whether a short course of the steroid methylprednisolone, taken as pills after knee replacement surgery, can reduce pain, the need for strong painkillers, and nausea. About 420 adults having their first knee replacement will be randomly assigned to receive either…

This study compares two knee braces for people with knee osteoarthritis. It looks at how the braces affect walking, pain, and daily function over 8 weeks. About 30 adults aged 40-85 with mild-to-moderate knee arthritis will participate. The goal is to find out which brace provide…

This study looks at whether turning a nerve stimulator on and off in short bursts can work as well as continuous stimulation for people with long-term pain from conditions like CRPS, radiculopathy, or peripheral neuropathy. About 30 adults who already have a spinal nerve stimulat…

This study looks at whether giving ICU doctors a special risk score (called ProVent-14) helps them more accurately predict if a patient on a breathing machine for two weeks will survive for one year. About 238 doctors, nurses, and other ICU staff will participate. The goal is to …

This study looks at whether the time of day a breathing test is done affects how quickly ICU patients can come off a ventilator. About 348 adults who have been on a ventilator for more than two days will be split into two groups: one gets the test early in the morning, the other …

This study tests whether showing people a bedside ultrasound of their heart in the emergency room helps them understand their risk for heart failure and motivates them to improve diet, exercise, and see a doctor. About 100 adults aged 45+ with high blood pressure, diabetes, or ob…

This study tests whether a new nerve monitoring device (NeuroVision) is better than standard hospital monitoring at preventing nerve injuries during spine surgery. About 148 adults having lateral spine surgery will be randomly assigned to one of the two monitoring methods. The ma…