Stem cells may boost ACL recovery in new trial
NCT ID NCT04650568
First seen Jan 08, 2026 · Last updated Jun 19, 2026 · Updated 30 times
Summary
This study tests whether adding a patient's own bone marrow stem cells during ACL reconstruction helps the new ligament heal better. One hundred adults with a recent ACL tear will receive either stem cells or a sham procedure. The main goal is to see if the graft looks healthier on MRI scans and if patients report better knee function.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Rush University Medical Center
Chicago, Illinois, 60521, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bone marrow derived mesenchymal stem cells
What this could lead to
If it works, this could lead to a standard way to improve ACL graft healing and reduce recovery time.
What could go wrong
This is an early-stage trial with only 100 participants, so results may not apply to everyone. The stem cell procedure also carries risks like infection or poor graft integration.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.