Ruijin Hospital

This study compares two different approaches for deciding whether to fix blocked heart arteries during planned heart valve surgery. It involves 792 adults who need valve surgery and also have narrowed heart arteries. One group uses a special computer analysis (QFR) to decide whic…

This study is testing a much shorter, one-week radiation treatment for breast cancer patients who need radiation to the breast area and nearby lymph nodes. The goal is to see if this condensed schedule is as effective at controlling the cancer while causing fewer side effects com…

This study is testing whether combining immunotherapy and targeted drugs with standard chemotherapy before surgery can better shrink tumors in people with advanced stomach or gastroesophageal junction cancer. The goal is to see if this approach leads to more complete tumor remova…

This study is testing whether adding two newer drugs (apatinib and camrelizumab) to standard chemotherapy helps people with advanced stomach cancer. The treatment is given both before surgery to shrink the tumor and after surgery to try to prevent the cancer from coming back. Res…

This study aims to see if a blood test that measures the immune system's strength against a common virus (CMV) can help doctors decide how long to give a preventive antiviral drug. It involves 250 adults who have received a stem cell transplant for blood cancer. The goal is to be…

This study is testing whether the drug TMF can safely control Hepatitis B virus in people who have normal liver enzyme levels. Researchers are enrolling 200 patients who have never received treatment before to see if TMF reduces virus levels and prevents liver damage. The trial c…

This is an early-stage clinical trial to test a new drug called CS01 in patients with advanced solid tumors that have spread. The main goals are to find a safe dose, check for side effects, and see if the drug shows any early signs of helping to shrink tumors. The study will enro…

This study looks back at how well CNCT-19 CAR-T cell therapy worked for 275 Chinese adults with B-cell acute lymphoblastic leukemia. Researchers are checking how many patients responded to treatment, how long remissions lasted, and what side effects occurred. The goal is to under…

This study is testing a new bedside imaging technology called Electrical Impedance Tomography (EIT) to help doctors better manage ventilator settings for patients with severe ARDS. By creating real-time pictures of air and blood flow in the lungs, researchers hope to find the saf…

This study is testing a personalized brain stimulation treatment for people with severe depression that hasn't improved with standard medications. Ten participants with special research electrodes already implanted in their brains will receive both real and fake stimulation in ra…

This study is testing if a drug called sirolimus can help control the severe inflammation and symptoms of Adult-Onset Still's Disease (AOSD) in patients who haven't improved with standard steroid treatments. It will involve just three patients with this rare, difficult-to-treat c…

This study wanted to test whether taking two common blood pressure medications after heart bypass surgery could help keep the new artery grafts from closing up. The trial planned to compare patients taking the medications for 24 weeks against those not taking them, checking graft…

This study is testing how well a new, detailed ultrasound imaging method can identify significant blockages in heart arteries. It involves 112 adults with suspected heart disease who are already undergoing a standard heart artery scan. The goal is to see if this new method can pr…

This study tested a special imaging scan called Electrical Impedance Tomography (EIT) to see if it could predict when a common oxygen therapy for breathing failure would stop working. Researchers monitored 90 adult patients in China who were receiving oxygen through a high-flow n…

This study is testing if the drug Idebenone can safely delay or prevent people with a specific sleep disorder (iRBD) from developing serious brain diseases like Parkinson's. About 142 participants will take either Idebenone or a placebo for five years. Researchers will track whet…

This study is testing whether a non-invasive brain stimulation technique called temporal interference stimulation (tTIS) can improve movement symptoms in people with early to mid-stage Parkinson's disease. Researchers will compare stimulation of two different brain areas to see w…

This study follows patients for 10 years after heart bypass surgery to understand the long-term effects of different blood-thinning medication strategies. Researchers want to know if taking two blood thinners for one year after surgery provides better protection against future he…

This study is looking back at the medical records of 102 adults with a type of blood cancer called B-cell acute lymphoblastic leukemia (B-ALL). Researchers want to understand how well and how safely the drug inotuzumab ozogamicin worked for these patients. No new treatments are b…

This study aims to understand how a specific gene, called TRIM25, behaves in the blood cells of people with sepsis compared to those without it. Researchers will collect blood samples from about 65 hospitalized patients to see if the activity of this gene is linked to how well pa…

This study is creating a new tool, called the SAH Index, to fairly compare how well different hospitals perform stomach cancer surgery. It uses existing medical records from 780 patients who had surgery in 2019 to account for differences in patient health before their operation. …

This study aims to understand if tracking how blood flows through the lungs of patients with severe ARDS can help predict their chances of survival. Researchers will use a special belt placed around the chest to take daily, non-invasive pictures of lung blood flow in 120 patients…