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New monitoring technique could personalize breathing support for ICU patients

NCT ID NCT07370610

Knowledge-focused Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 120 adults with moderate-to-severe ARDS who are on a breathing machine. Researchers use a non-invasive belt (electrical impedance tomography) to track how air and blood flow are distributed in the lungs over time. The goal is to see if different lung function patterns are linked to survival at 28 days, which could help doctors tailor ventilator settings to each patient.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors personalize ventilator settings for ARDS patients based on real-time lung function, potentially improving survival.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test a new therapy, and results may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

ARDS Mechanically Ventilated Patients

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ge ≥ 18 years * Moderate-to-severe ARDS (Berlin definition, PaO₂/FiO₂ ≤ 200 mmHg) * Mechanically ventilated and eligible for EIT monitoring * Informed consent obtained from patient or legal surrogate Exclusion Criteria: * Pregnancy * Presence of implanted metallic devices interfering with EIT (e.g., pacemaker) * Severe chest wall deformity or skin condition preventing electrode placement * Expected survival \< 24 hours

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARDS Mechanically ventilated patients

Contacts and locations

Locations

  • Department of Critical Care Medicine，Ruijin Hospital，Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200025, China

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