Rennes University Hospital

This study tests whether the blood thinner rivaroxaban can prevent strokes in people with hypertrophic cardiomyopathy (HCM) who have early signs of heart strain but no irregular heartbeat. About 532 adults aged 40-80 with HCM and abnormal left atrial strain will be randomly assig…

This study tests a new, intensive brain stimulation technique for people aged 65 and older who have depression that hasn't improved with medication and also have memory or thinking problems. The treatment uses personalized magnetic pulses to target a specific brain area. The goal…

This study looks at whether giving lidocaine (a numbing medicine) through a vein during and after liver surgery can lower the chance of opioid-related side effects like nausea, vomiting, and breathing problems. About 312 adults having planned open liver surgery will be randomly a…

This study looks at how the brain changes and reorganizes after a stroke that causes arm weakness. Researchers will use MRI scans to track brain activity and connections in 30 adults over six months. The goal is to learn why some people recover better than others, which may help …

This study looks at how many people scheduled for back surgery for lumbar spinal stenosis also have peripheral artery disease (PAD) in their legs, which can cause similar symptoms like leg pain. About 49 participants will get a special CT scan to check for PAD, plus several routi…

This study looks at whether being admitted to a hospital bed that doesn't match what the emergency doctor recommended affects a patient's chance of dying. Researchers will follow about 2,766 adults who need to be hospitalized after an ER visit. The goal is to see if the right bed…

This study looks at 100 people with moderate to severe traumatic brain injury to see if special MRI scans can help predict how well they will recover after one year. Participants get an extra MRI scan, but no change to their treatment. The goal is to find better ways to understan…

This study looks at how chemotherapy for Hodgkin lymphoma may change sperm DNA and affect fertility in men aged 18 to 45. Researchers will analyze sperm samples before and after treatment to understand long-term effects on the epigenome. The goal is to learn whether these changes…