Rennes University Hospital

This study tests whether rituximab, an older and less expensive drug, works as well as ocrelizumab for people with relapsing-remitting multiple sclerosis. About 386 adults aged 18-55 with active MS will receive either drug and be followed for 2 years. The main goal is to see if r…

This study tests whether giving a protein called albumin after a liver transplant can lower the risk of acute kidney injury. About 400 adult liver transplant recipients will be split into two groups: one gets enough albumin to keep blood levels above 30 g/L for five days, while t…

This study compares two types of keyhole surgery for womb cancer: robot-assisted and standard laparoscopy. About 1,680 women with early-stage womb cancer will be randomly assigned to one of the two methods. The goal is to see which approach is more cost-effective and leads to bet…

This early-stage study tests whether repeated injections of stem cells from donated fat tissue are safe for people with primary progressive multiple sclerosis (MS), a form that steadily worsens. Ten adults aged 18–55 with moderate disability will receive the cells directly into t…

This study tests whether a brain-training technique called EEG neurofeedback can improve arm movement when started soon after a stroke. About 40 adults who had a stroke within the past 3 weeks will either get real or fake neurofeedback alongside standard rehab. The goal is to see…

This study tests a type of hypnotherapy called E2R for people with chronic insomnia. It compares E2R to usual care (often sleep medications) to see if hypnosis can improve sleep without side effects. About 136 adults with long-term sleep problems will take part. The goal is to fi…

This study is testing whether a new, low-cost brain scan can find early signs of Alzheimer's and Parkinson's disease. Researchers will compare brain scans from 120 people — including those at risk for Alzheimer's, those with Parkinson's, and healthy volunteers — to see if they ca…

This study looks at why some children with B-cell acute lymphoblastic leukemia (B-ALL) relapse after treatment. Researchers will collect blood and bone marrow samples from 50 newly diagnosed children at three key times during therapy. They aim to understand how a protein called C…

This study looks at whether patients who take antiplatelet drugs (like aspirin) and have a minor head injury but no other signs of brain bleeding can safely skip a CT scan. Current guidelines often send these patients for a scan, but the benefit is unclear. Researchers will follo…

This study looks at whether two substances found in urine (TIMP-2 and MMP-2) can help predict kidney damage in people with spina bifida. Researchers will compare these biomarkers with the standard Galloway score, which requires invasive testing. About 50 participants will provide…

This study tests whether temporarily covering the eyes of the medical team leader during simulated emergencies can improve how the team works together. About 54 experienced doctors and nurses will take part in high-fidelity simulations. The goal is to see if this unusual training…

This study is testing a new, non-invasive MRI technique to find early brain changes linked to Alzheimer's disease. Researchers will scan the brains of 50 people with mild memory concerns and compare them to healthy volunteers. The goal is to develop a simple, affordable way to id…

This study tests a new set of rules for treating neck injuries in conscious, stable patients before they reach the hospital. The goal is to see if these rules can reduce unnecessary neck immobilization and imaging, and improve how patients are routed through the healthcare system…