Regeneron Pharmaceuticals

This study looked at whether giving a COVID-19 antibody treatment (casirivimab+imdevimab) along with the Moderna vaccine changes how well the vaccine works. About 295 healthy adults took part. The goal was to see if the timing between the antibody treatment and the vaccine matter…

This study looked at how well the drug cemiplimab works for people with advanced skin cancers (squamous cell or basal cell carcinoma) in real-world settings, not just in controlled trials. Researchers tracked 287 patients to measure tumor shrinkage, survival, side effects, and qu…

This study tested an experimental drug called REGN7544 in 76 adults hospitalized with sepsis and low blood pressure. The goal was to see if the drug could safely reduce the need for standard blood pressure medications (vasopressors). Researchers measured how much vasopressor pati…

This early-stage study tested the safety of a combination of two antibodies (casirivimab and imdevimab) against the COVID-19 virus. It involved 45 healthy adults or those with stable chronic conditions. The goal was to see if the treatment is safe and how the body processes it.

This study tested a drug called cemiplimab given before surgery to people with stage II to IV cutaneous squamous cell carcinoma (a type of skin cancer). The goal was to see if the drug could eliminate or shrink the tumor before surgery. 79 participants received the treatment, and…

This study tested an experimental drug called ALN-APOC3 in 32 adults with dyslipidemia (abnormal levels of fats in the blood). The main goal was to check the drug's safety and how the body processes it. Researchers also looked at how the drug changes cholesterol and other fat lev…

This study tested a new drug called REGN4461 in 16 people with generalized lipodystrophy, a rare condition where the body can't store fat properly, leading to serious metabolic problems like diabetes and high triglycerides. The drug aims to improve blood sugar and fat levels by m…

This study tested a drug called dupilumab in 106 adults with bullous pemphigoid, a painful blistering skin condition that mostly affects older people. The goal was to see if dupilumab could help patients stop taking steroids and keep the disease under control. Results showed whet…

This study tested a new immunotherapy drug, cemiplimab, against standard chemotherapy for people with advanced non-small cell lung cancer that has a specific marker (PD-L1). About 700 patients participated. The goal was to see if cemiplimab helps people live longer and keeps the …

This study looked at how well the drug dupilumab works for people with skin of color who have moderate-to-severe eczema (atopic dermatitis). 124 adolescents and adults received the drug for 24 weeks. The main goal was to see if their eczema improved by at least 75%, and the study…

This study tested a new drug called REGN5459 in 43 people with multiple myeloma that had come back or stopped responding to other treatments. The drug is a bispecific antibody that helps the immune system attack cancer cells. The goal was to check safety and see if the drug could…

This early-phase study tested an experimental drug called cemiplimab, injected directly into skin tumors before surgery. The goal was to see if it is safe and how well it shrinks two types of skin cancer: squamous cell carcinoma and basal cell carcinoma. 97 adults with recurrent,…

This study tested a combination of an immunotherapy drug (cemiplimab) and a vaccine (ISA101b) in 113 adults with advanced HPV16-positive cervical cancer that had worsened after standard chemotherapy. The goal was to see if the combination could shrink tumors and improve survival.…

This study tested whether adding the immunotherapy drug cemiplimab to standard chemotherapy helps people with advanced non-small cell lung cancer live longer. About 789 participants received either the combination or chemotherapy alone. The goal was to see if the combo improves s…

This early-stage study tested a new drug called odronextamab (REGN1979) in 200 adults with B-cell blood cancers like non-Hodgkin lymphoma and chronic lymphocytic leukemia that had stopped responding to standard treatments. The goal was to check the drug's safety and find the righ…

This study tested a drug called dupilumab in 102 children with active eosinophilic esophagitis (EoE), a condition where the esophagus becomes inflamed, making swallowing painful. The goal was to see if dupilumab could reduce inflammation better than a placebo after 16 weeks. Rese…

This study tested an experimental drug called REGN7508 in 179 adults having knee replacement surgery. The goal was to see if it could prevent dangerous blood clots (venous thromboembolism) better than standard care. Researchers also monitored side effects and how the drug behaves…

This study tested two experimental drugs (REGN9933 and REGN7508) to see if they can prevent blood clots in adults who need a PICC line—a tube placed in a vein for medical treatment. About 195 participants received either the drug or a placebo. The goal was to check how well the d…

This study tested two experimental drugs, REGN1908 and REGN1909, mixed together to reduce eye allergy symptoms in people with cat allergies. 64 participants received either the drug or a placebo to see if it safely lessens itching and redness. The goal is to ease symptoms, not cu…

This study tested two experimental drugs, REGN5713 and REGN5715, given together to reduce eye allergy symptoms caused by birch pollen. 54 adults with a history of moderate to severe birch pollen allergy received either the drug or a placebo. The main goal was to see if the drug c…

This study looked at medical records of about 290,000 people in the US who received aflibercept (Eylea) eye injections to treat various retinal diseases. The goal was to find out how often retinal vasculitis, a type of eye inflammation, occurred after the injections. Researchers …

This study examined over 550,000 patients to find out how often retinal vasculitis (inflammation of blood vessels in the eye) occurs after treatment with aflibercept (Eylea®). Researchers reviewed medical records to confirm cases and identify types of vasculitis. The goal was to …

This early-stage study tested a new drug called REGN9533 in 72 healthy adults to see if it is safe and how the body handles it. The drug targets a clotting protein and may one day help prevent dangerous blood clots. No treatment was given—this trial only gathered safety and dosin…

This study tracked 581 pregnant women to see if the drug dupilumab (used for eczema or asthma) affects pregnancy or baby health. It compared women who took dupilumab to those with the same diseases who did not, and to healthy pregnant women. The goal was to check for birth defect…