Radboud University Medical Center

This study tests whether using personalized dosing (based on drug levels in the blood) helps more patients with bacterial infections reach the right amount of teicoplanin compared to standard dosing. About 74 adults in hospital intensive care or other units will take part. The go…

This study tests whether a 12-month lifestyle program focusing on stress, exercise, nutrition, sleep, and self-management can improve quality of life for people with Parkinson's disease. 256 participants will either work on their goals independently or with a lifestyle coach. The…

This study tests whether adding a drug called interferon-gamma to standard antifungal therapy helps adults with candidemia, a severe fungal blood infection, clear the infection faster. About 200 participants will receive either standard care alone or standard care plus the study …

This study tests whether colchicine, an anti-inflammatory medicine, can slow the worsening of aortic valve stenosis—a common heart valve condition. About 150 adults with moderate, symptom-free valve narrowing will take colchicine or a placebo for up to 2 years. The goal is to see…

This study tests whether a year-long mindfulness-based therapy can reduce stress, anxiety, and depression in 174 people with Parkinson's disease. Participants are randomly assigned to either the mindfulness program or their usual care. The goal is to see if lowering stress improv…

This study tests whether a smartphone app can help older adults increase their protein intake using everyday foods. The goal is to preserve muscle mass and strength, which are key for healthy aging. Researchers will enroll 140 participants who are comfortable using a smartphone a…

This study tracks 350 ICU patients with severe influenza to see how often they develop a serious fungal lung infection called aspergillosis. Researchers aim to identify patient and virus-related risk factors. The goal is to better understand and potentially prevent this complicat…

This study looks at whether electroconvulsive therapy (ECT) or antidepressant medication is more cost-effective for treating severe major depression. Researchers will follow 220 adults in the Netherlands who have not gotten better with at least one antidepressant. The goal is to …