Queen Mary University Of London

This study is for people in Pakistan with hepatitis C whose first treatment didn't work. It compares two different medication plans to see which one clears the virus better. About 318 adults will take part, and the goal is to find a safe, effective second-line option.

This study tests whether cladribine tablets, given over two years, can protect hand function in people with advanced multiple sclerosis (MS). About 204 adults with significant disability (EDSS 6.5-8.5) will receive either cladribine or a placebo. The goal is to see if the drug sl…

This study tests whether adding a drug called ipatasertib to standard chemotherapy and immunotherapy helps shrink or eliminate aggressive triple-negative breast tumors before surgery. About 146 women with newly diagnosed, high-risk breast cancer will participate. The main goal is…

This study tests whether giving an antimicrobial treatment to children recovering from severe acute malnutrition can reduce their risk of death, re-hospitalization, or failure to regain healthy weight. About 674 children aged 6-59 months who are hospitalized with complicated maln…

This study tests whether adding a drug called ATRA (a form of vitamin A) to standard chemotherapy can help people with locally advanced pancreatic cancer live longer without their disease getting worse. About 170 participants will receive either chemo alone or chemo plus ATRA. Th…

This study tests a new stent valve (TRICENTO) in 15 people with carcinoid heart disease who have a severely leaky tricuspid valve and cannot have open-heart surgery. The goal is to see if the implant can reduce the leak and improve symptoms and quality of life. Participants will …

This study is testing a new blood test that looks for the TB bacteria itself, rather than the body's immune response. Current tests can't tell if treatment for dormant TB worked, or who will get sick later. Researchers will test 100 people with and without dormant TB to see if th…

This study is working on a new way to detect pancreatic cancer earlier using a simple urine or blood test. Researchers are collecting samples from 3500 people with and without pancreatic disease to see if a panel of biomarkers can accurately identify cancer. The goal is to create…

This study looks at a new blood test that uses DNA sequencing to quickly identify the bacteria causing infective endocarditis, a serious heart infection. Current methods take up to 5 days to grow bacteria from blood samples, delaying the right treatment. The new test aims to give…

This study looked back at 3350 men with early-stage prostate cancer who chose watchful waiting instead of immediate treatment. Researchers analyzed medical records and biopsy samples to find which factors, like PSA levels and Gleason scores, best predict how the disease will prog…

This study looks at whether a drug called Racecadotril can reduce fluid leakage in skin blisters caused by a chemical. The blisters mimic some aspects of lung injury in ARDS, a severe condition where lungs fill with fluid. 48 healthy volunteers will receive either the drug or a p…

This study tests a wearable sensor that measures lactate levels through the skin, comparing it to standard blood tests in 20 patients recovering from heart bypass or valve surgery. The goal is to see if the sensor can reduce the need for frequent blood draws and provide more comf…

This study tests a new way of organizing care for chronic diseases like high blood pressure, diabetes, and kidney disease in Thailand. Researchers will work with 16 primary care clinics to see if using patient data in real time helps doctors and nurses provide better care. The go…

This study tests whether a computer model can look at images of skin cancer tissue and predict how the disease will progress. Researchers will analyze samples from 300 patients with a type of skin cancer called squamous cell carcinoma. The goal is to see if the AI can spot which …

This study looks at how common high-risk HPV is in transgender people and whether self-collected samples (from the vagina, anus, urine, or mouth) work as well as clinician-collected ones. About 100 transgender men and women will take their own samples and answer a survey about co…