Queen Mary University Of London

This trial is testing if adding a repurposed drug called ATRA to standard chemotherapy (gemcitabine and nab-paclitaxel) is more effective for controlling locally advanced pancreatic cancer. About 170 patients will be randomly assigned to receive either the standard two-drug combo…

This large trial is testing whether adding extra support helps children survive and recover after being hospitalized for severe malnutrition. Researchers are comparing standard care against two extra packages: one gives children antibiotics to prevent infections, and the other pr…

This study aims to find the best second treatment for people in Pakistan whose Hepatitis C infection did not clear after their first round of antiviral drugs. It will compare two different lengths of a follow-up drug combination (12 weeks vs. 24 weeks) in about 318 adults. The go…

This UK trial is testing whether a drug called cladribine can slow the loss of arm and hand function in people with advanced multiple sclerosis (MS). Over two years, about 200 participants will receive either the drug or a placebo to see which better protects their ability to per…

This study is testing a new, painless skin sensor that measures lactate levels without needles. It will be worn by 20 patients recovering from elective heart bypass or valve surgery for up to 14 hours. The goal is to see if the sensor's readings match those from standard blood te…

This study is testing a new computer program (AI) that analyzes microscope images of skin cancer tissue. The goal is to see if the AI can accurately predict which cancers are most likely to spread to other parts of the body. Researchers are using tissue samples from 300 patients …

This study is evaluating a new blood test designed to detect the bacteria that cause dormant tuberculosis (TB) infection. Current tests can't tell if someone has been cured after treatment or identify which infected people will actually get sick. Researchers will test 250 people,…

This study is testing a new blood test that reads bacterial DNA to quickly identify the specific germ causing a serious heart valve infection called infective endocarditis. The goal is to see if this new test is as accurate as the current standard method, which can take up to fiv…

This study is testing if a daily capsule containing bacterial proteins can prevent wheezing in infants who were recently hospitalized for severe bronchiolitis. Researchers will give the capsule or a placebo to about 173 infants for up to two years to see if it reduces the number …

This study analyzed medical records and tissue samples from over 3,300 men diagnosed with early-stage prostate cancer between 1990 and 2006 who chose watchful waiting (no immediate treatment). Researchers looked back at these cases to identify which factors—like PSA levels, cance…

This study is exploring if self-collected samples (like vaginal swabs, urine, and mouthwash) are a good and acceptable way to check for high-risk HPV in transgender people. It aims to understand how common HPV is in this community and if self-testing could make cancer screening m…