Ohsu Knight Cancer Institute

This study tests a new treatment for people with advanced liver cancer that cannot be removed by surgery. The treatment combines a type of internal radiation (Y-90) with three drugs that help the immune system fight cancer and block tumor growth. The goal is to see if this combin…

This early-phase study tests a drug called 177Lu-DOTATATE in 10 people with stage IV or recurrent breast cancer. The drug targets cancer cells that have a specific marker (SSTR2) and delivers radiation to kill them. The goal is to see if it can shrink tumors and reduce cancer ste…

This early-phase trial tests whether giving ruxolitinib followed by ruxolitinib plus azacitidine after a stem cell transplant can safely prevent graft-versus-host disease (GVHD) and keep acute myeloid leukemia (AML) from coming back. About 40 adults with AML in remission will tak…

This early-phase study tests whether removing the entire pancreas and transplanting the patient's own insulin-making cells into the liver can safely treat benign pancreatic tumors and chronic pancreatitis without causing diabetes. About 12 adults with non-cancerous pancreatic gro…

This study tests whether taking a pill called ulipristal acetate before a mammogram can temporarily lower breast density in premenopausal women with extremely dense breasts. Dense tissue can hide cancers on mammograms, so the goal is to make screening more accurate. About 26 part…

This study tests if a single dose of gruticibart can prevent blood clots that often form when a catheter is placed in a vein. About 90 adults getting a catheter will receive the drug and be monitored for clots and bleeding. The goal is to reduce pain and swelling while avoiding t…

This study tests a supervised exercise program called Exercise Together for people with primary brain tumors and their caregivers. The program uses partner exercises to improve daily functioning and teamwork. Researchers want to see if it is safe, doable, and helpful for mental a…