Ohsu Knight Cancer Institute
Clinical trials sponsored by Ohsu Knight Cancer Institute, explained in plain language.
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New drug combo shrinks tumors before surgery in early trial
Disease control CompletedThis early-phase study tested the safety and best dose of two drugs, abemaciclib and niraparib, given together before surgery for a common type of breast cancer (HR+ HER2-). The goal was to see if this combination could shrink tumors before they are removed. Only 8 people took pa…
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New program aims to ease pain after head and neck cancer
Symptom relief CompletedThis study tested an improved pain management program for people who finished treatment for head and neck cancer. The goal was to help with pain, mood, and daily activities. 33 survivors took part to see if the program could improve their quality of life.
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Pre-Surgery workouts boost recovery in head and neck cancer patients
Symptom relief CompletedThis study tested whether a simple exercise program before head and neck cancer surgery could help patients get back on their feet faster. 52 adults scheduled for major surgery did daily walking, sit-to-stand, and other exercises for a few weeks before their operation. The goal w…
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Forest in a bottle: scented oils may boost immunity after cancer treatment
Knowledge-focused CompletedThis study tested whether breathing in scented oils (like wood or fragrant oils) could help improve immune cells in people who finished treatment for breast or prostate cancer. The goal was to see if this approach is practical and can be used in future research. 28 participants t…
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 26, 2026 06:08 UTC
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Can a simple test predict chemotherapy falls?
Knowledge-focused CompletedThis study followed 200 adults aged 40-85 with cancer who were about to start chemotherapy. Researchers measured symptoms like numbness, disability, and daily activity to find simple tests that could predict when patients are at higher risk for falls and loss of function. The goa…
Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 26, 2026 06:00 UTC
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Doctor training may spot skin cancer sooner
Knowledge-focused CompletedThis study looked at whether a special training program for primary care doctors could help them better find and treat early-stage melanoma, a serious skin cancer. Fifty-four doctors from two clinics took part. The goal was to see if the training improved their knowledge and skil…
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 26, 2026 05:50 UTC