Nuvasive
Clinical trials sponsored by Nuvasive, explained in plain language.
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New spinal implants tested for chronic back pain relief
Disease control CompletedThis study evaluated the safety and effectiveness of two expandable spinal implants (MLX and XLX ACR) for people with degenerative back conditions like disc disease and spondylolisthesis. Researchers followed 109 patients who had already received these implants during standard sp…
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Stem cell bone graft tested to heal spinal fusions faster
Disease control CompletedThis study tested a special bone graft material called Osteocel Plus, which contains stem cells, during spinal fusion surgery. The goal was to see if it helps the spine bones grow together solidly after surgery for people with severe, chronic lower back pain. Researchers followed…
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Stem cell bone graft tested to heal spinal fusions
Disease control CompletedThis study tested a special bone graft material containing stem cells, called Osteocel Plus, to see how well it helps spinal bones grow together after fusion surgery for severe back pain. Researchers followed 28 patients with degenerative disc disease for two years after surgery …
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Stem cell graft aims to heal spinal fusions faster
Disease control CompletedThis study tested a special bone graft material containing stem cells, called Osteocel Plus, for use in spinal fusion surgery. The goal was to see if it helps the bones in the spine join together solidly after surgery for severe, long-term back pain. Researchers followed 19 patie…
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New artificial neck disc tested as alternative to spinal fusion
Disease control CompletedThis study tested whether a new two-level artificial neck disc (Simplify Disc) is as safe and effective as the standard spinal fusion surgery for treating severe neck and arm pain. It involved 182 adults with worn discs in two adjacent neck vertebrae who hadn't improved with othe…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New bone graft tested to speed recovery from neck surgery
Disease control CompletedThis study tested a bone graft product called Osteocel Plus in people having neck surgery for severe, painful disc disease. Doctors used it during a common fusion procedure to see how well and how quickly it helped the bones grow together. Researchers followed 182 patients for tw…
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Stem cell bone graft aims to heal spinal fusions faster
Disease control CompletedThis study tested a special bone graft material containing stem cells, called Osteocel Plus, during a specific type of spinal fusion surgery (XLIF). The goal was to see if this material could help the spine bones fuse together solidly and potentially faster than other standard gr…
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New spinal implant tested for safety and effectiveness
Disease control CompletedThis study tested the safety and performance of the Modulus ALIF system, a medical device used in spinal fusion surgery. Researchers followed 123 patients with degenerative disc disease, spondylolisthesis, or spinal stenosis who received the implant. They checked for complication…
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New artificial disc aims to replace painful neck fusion surgery
Disease control CompletedThis study tested a new artificial neck disc called NeoDisc against the standard spinal fusion surgery for people with a single worn-out neck disc causing pain and nerve problems. It aimed to see if the new disc was as safe and effective as fusion over two years, potentially allo…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New disc implant tested as alternative to spinal fusion
Disease control CompletedThis study tested a new artificial disc called the Simplify Disc to see if it was as safe and effective as the standard spinal fusion surgery for treating severe neck and arm pain from a single worn disc. It involved 150 adults whose pain did not improve with other treatments lik…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Artificial neck disc shows lasting relief in 5-Year study
Disease control CompletedThis study followed 291 people for five years after they received an artificial disc implant for neck pain caused by worn-out spinal discs. The goal was to see if the implant remained safe and effective long-term by measuring pain, disability, and overall health. Results showed t…
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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3D-Printed spine implant tested for back pain relief
Disease control CompletedThis study tested the safety and performance of a new 3D-printed titanium implant used during a specific type of spinal fusion surgery. It involved 36 adults with degenerative back conditions like disc disease or scoliosis. Researchers checked for complications, used CT scans to …
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Artificial neck disc shows Long-Term promise over fusion surgery
Disease control CompletedThis study followed 145 patients for five years after receiving an artificial neck disc (Simplify Disc) to treat painful degenerative disc disease. It compared the long-term safety and effectiveness of the disc implant to traditional spinal fusion surgery. Researchers measured pa…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Mar 16, 2026 15:27 UTC
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New bone putty tested to avoid painful hip bone harvest in spine surgery
Disease control CompletedThis study tested whether a synthetic bone graft material called AttraX Putty works as well as using a patient's own bone taken from their hip for spinal fusion surgery. It involved 45 adults with chronic lower back pain who needed a specific type of minimally invasive spine surg…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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New nerve monitor aims to make back surgery safer
Diagnosis CompletedThis study tested a new method to monitor nerve health during a specific type of minimally invasive back surgery (XLIF). The goal was to see if stimulating nerves near the spine during the operation could give surgeons better, real-time warnings to help prevent nerve damage. Rese…
Sponsor: NuVasive • Aim: Diagnosis
Last updated Apr 01, 2026 14:42 UTC
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New surgical tool aims to stop spine screw mistakes before they happen
Diagnosis CompletedThis study tested a new feature of a nerve monitoring system used during spinal fusion surgery. The system gives surgeons real-time alerts about nerve safety while placing screws, instead of checking after the screw is already in place. Researchers wanted to see if this real-time…
Sponsor: NuVasive • Aim: Diagnosis
Last updated Mar 30, 2026 14:29 UTC
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Back surgery showdown: which procedure works best?
Symptom relief CompletedThis study compared two different surgical methods for treating a slipped vertebra in the lower back. Researchers wanted to see which procedure—XLIF or TLIF—worked better to reduce pain and improve function over two years. The study involved 55 adults whose back pain hadn't impro…
Sponsor: NuVasive • Aim: Symptom relief
Last updated Apr 04, 2026 03:21 UTC
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New spinal implant aims to ease chronic back pain
Symptom relief CompletedThis study tested a new spinal implant system designed to help people with degenerative back conditions like disc disease and scoliosis. It involved 75 adults who had spinal fusion surgery using the implant. Researchers followed patients for two years to see if the device was saf…
Sponsor: NuVasive • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Less invasive back surgery under the microscope
Symptom relief CompletedThis study compared two surgical techniques for spinal fusion to treat painful degenerative disc disease in the lower back. Researchers followed 67 patients who received either traditional open surgery or a newer, less invasive approach. The goal was to see if the newer technique…
Sponsor: NuVasive • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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New back surgery technique aims to ease pain with smaller incision
Symptom relief CompletedThis study tested a less invasive spinal fusion surgery for people with painful, worn-out discs in their lower back. The procedure uses a smaller incision than traditional surgery, aiming to reduce pain and disability after the operation. Researchers followed 77 patients for two …
Sponsor: NuVasive • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Massive spine surgery database aims to find best treatments
Knowledge-focused CompletedThis study created a large database to track the results of spine surgeries for conditions like degeneration, deformity, and trauma. It followed over 8,000 patients who were candidates for surgery to collect information on their recovery and outcomes. The goal was to compare diff…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Scientists test new way to 'Listen' to nerves during spine operations
Knowledge-focused CompletedThis study tested a new method to monitor nerve function during surgery for degenerative lower back disc disease. Researchers placed electrodes on the skin over the lower back to stimulate nerves and recorded muscle responses in the legs. The goal was to see if this approach was …
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Doctors test High-Tech planning to improve spine surgery results
Knowledge-focused CompletedThis study tested whether using special computer software to plan spine surgeries leads to better outcomes. Surgeons used the software before and during surgery to help achieve proper spinal alignment. Researchers followed 306 patients to see if this detailed planning approach im…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Researchers track nerve safety in back surgery
Knowledge-focused CompletedThis study aimed to understand how well nerve monitoring works during a specific type of spinal fusion surgery. It involved 323 adults with severe, long-term back pain who were scheduled for the procedure. Researchers tracked the patients' nerve function during and after surgery …
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Can a computer predict your posture after back surgery?
Knowledge-focused CompletedThis study tested a new computer modeling tool designed to predict how a patient's posture will look after spinal fusion surgery. Researchers used the tool on 200 adults who had already undergone the procedure to see if its predictions matched their actual post-surgery X-rays. Th…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:47 UTC