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5-Year study confirms disc implant keeps neck pain at bay

NCT ID NCT04980378

First seen Jan 11, 2026 · Last updated May 18, 2026 · Updated 16 times

Summary

This study followed 291 people who received a two-level Simplify® Cervical Artificial Disc to treat degenerative disc disease in the neck. Researchers checked how well the disc worked over 5 years by measuring pain, nerve function, and whether any serious problems or repeat surgeries occurred. The goal was to confirm the disc is safe and effective for long-term use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Buffalo Spine Surgery

    Lockport, New York, 14094, United States

  • Carolina Neurosurgery and Spine Associates

    Charlotte, North Carolina, 28204, United States

  • Connecticut Orthopaedic Specialists

    Hamden, Connecticut, 06518, United States

  • Indiana Spine Group

    Carmel, Indiana, 46032, United States

  • Kennedy-White Orthopedic Center

    Sarasota, Florida, 34232, United States

  • NorthShore University Health System

    Evanston, Illinois, 60201, United States

  • Oregon Neurosurgery

    Springfield, Oregon, 97477, United States

  • Orthopaedic Education and Research Institute of Southern California

    Orange, California, 92868, United States

  • Orthopaedic Institute of Western Kentucky

    Paducah, Kentucky, 42003, United States

  • Parkview Research Center

    Fort Wayne, Indiana, 46845, United States

  • Spine Education and Research Foundation

    Thornton, Colorado, 80229, United States

  • Spine Institute of Louisiana

    Shreveport, Louisiana, 71101, United States

  • Texas Back Institute

    Plano, Texas, 75093, United States

  • Texas Spine Consultants

    Addison, Texas, 75001, United States

  • The Disc Replacement Center

    West Jordan, Utah, 84088, United States

  • The Spine Institute for Spine Restoration

    Santa Monica, California, 90403, United States

  • Virginia Spine Institute

    Reston, Virginia, 20191, United States

  • William Beaumont Hospital Research Institute

    Royal Oak, Michigan, 48073, United States

Conditions

Explore the condition pages connected to this study.