Mcmaster University
Clinical trials sponsored by Mcmaster University, explained in plain language.
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Can fewer eye injections keep vision safe? new study tests flexible dosing
Disease control OngoingThis study tests a flexible 'treat and extend' approach for faricimab injections against the standard fixed schedule in people with diabetic macular edema. About 446 adults with vision loss from this condition will receive either schedule to see if the flexible plan works just as…
Phase: PHASE4 • Sponsor: McMaster University • Aim: Disease control
Last updated May 26, 2026 09:43 UTC
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Shoulder surgery showdown: which fix keeps the joint in place?
Disease control OngoingThis study compares two surgical procedures for people who have repeated shoulder dislocations. One hundred fourteen adults aged 18-50 with at least two dislocations will receive either a Bankart repair (sometimes with a Remplissage) or a Latarjet procedure. The main goal is to s…
Phase: NA • Sponsor: McMaster University • Aim: Disease control
Last updated May 26, 2026 09:42 UTC
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Can exercise and education keep back pain from taking over your life?
Disease control OngoingThis study looks at a program called Back to Living Well for adults with long-term low back pain. The program combines exercise with education on self-management, offered online or in person at local YMCAs. Researchers want to see if it helps reduce disability and pain flares. Ab…
Sponsor: McMaster University • Aim: Disease control
Last updated May 26, 2026 09:26 UTC
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New ultrasound technique could replace surgery for diagnosing common endometriosis
Diagnosis ENROLLING_BY_INVITATIONThis study tests a new, non-invasive ultrasound technique called SPG to diagnose superficial endometriosis, the most common form of the disease. Currently, diagnosis requires surgery, but this method uses fluid to make tiny lesions visible on ultrasound. Researchers will compare …
Sponsor: McMaster University • Aim: Diagnosis
Last updated May 26, 2026 09:26 UTC
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New light therapy could ease C-Section pain without extra drugs
Symptom relief OngoingThis study looks at whether a special light and laser device, used on the wound twice a day, can help reduce pain after a planned C-section. The goal is to find a drug-free way to manage pain, especially since strong painkillers can affect the baby. About 180 women will take part…
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated May 26, 2026 09:41 UTC
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Talking therapy for dads: a new hope for perinatal depression?
Symptom relief OngoingThis study tests whether a 9-week online group therapy program (cognitive behavioural therapy) can help fathers and non-birthing parents who have depression during their partner's pregnancy or the first 18 months after birth. 48 participants in Ontario will be randomly assigned t…
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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New program aims to bring comfort, not hospitals, to dying seniors
Symptom relief OngoingThis study tests a program called SPA-LTC that helps long-term care staff provide better palliative (comfort) care for frail elderly residents. About 594 residents and their families will take part. The goal is to see if the program reduces trips to the hospital and improves sati…
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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New online therapy aims to lift the fog of postpartum depression
Symptom relief OngoingThis study tests whether a 10-week online group therapy program (cognitive behavioural therapy) can help mothers and birthing parents with postpartum depression or anxiety. About 48 participants in Ontario will be randomly assigned to either receive the online therapy plus usual …
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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Moms helping moms: new study tests nurse-peer therapy for postpartum depression
Symptom relief OngoingThis study tests whether a 9-week online group therapy program, co-led by public health nurses and mothers who have recovered from postpartum depression, can reduce depression symptoms in new mothers. About 170 mothers in Ontario with an infant under 12 months and elevated depres…
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated May 18, 2026 12:08 UTC
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Teen sports specialization may shape hips for life
Knowledge-focused OngoingThis study follows 201 teens aged 12-14 over two years to see if focusing on a single sport affects hip development and leads to a condition called femoroacetabular impingement (FAI), where hip bones rub together. Participants will have MRI scans and fill out questionnaires. The …
Sponsor: McMaster University • Aim: Knowledge-focused
Last updated May 26, 2026 09:31 UTC
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Dementia prevention web study pulled before starting
Knowledge-focused TerminatedThis study was designed to see if an internet-based course could teach Canadians without dementia about ways to reduce their risk. Participants would have been split into two groups: one taking the dementia prevention course and the other taking a different health lesson. The stu…
Phase: NA • Sponsor: McMaster University • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC