Mclean Hospital

This study tested a smartphone app made just for women with opioid use disorder. The goal was to see if the app was easy to use and helpful for staying on medication treatment. 39 women who had recently started medication took part. The results will show if this digital tool can …

This study tested a computer-based cognitive training program in 72 adults with bipolar disorder who also had psychosis. The goal was to see if the training could improve memory, attention, and problem-solving skills compared to a control computer activity. Participants were with…

This study aimed to find out which antidepressant works best for people with depression and loss of interest (anhedonia) by using brain scans and behavior tests. 133 adults with major depression took part. The goal was to predict the best treatment before starting medication, usi…

This study followed 100 healthy girls aged 12-14 and their mothers for six months to see if brain activity and genetics can predict depression. The girls had interviews, computer tasks, saliva tests, and an fMRI brain scan. The goal was to understand early warning signs, not to t…

This study tested whether reviewing patients' electronic messages (like texts and emails) with their therapist could improve mental health care. About 110 adults with anxiety or depression took part. Researchers measured changes in quality of life and the strength of the therapis…

This study looked at 164 teenage girls aged 13-19 with painful periods to understand how their brains process pain. Researchers used brain scans and pain tests to find patterns that might predict if short-term menstrual pain turns into long-term chronic pain. The goal is to learn…

This study looked at whether the McLean Anxiety Mastery Program helps children and teens ages 6 to 19 with anxiety disorders like social anxiety, panic, or phobias. Researchers collected surveys from patients before, during, and after treatment, and compared them to kids on a wai…

This pilot study tested a telehealth program called CRAFT-EP for families of people with early psychosis who also use alcohol or cannabis. 65 family members took part to see if the program could improve their wellbeing, including reducing depression and anxiety. The goal was to l…

This study looked at how acute stress and negative emotions influence eating behavior in women with binge-eating disorder. Researchers used brain scans to measure activity in reward and self-control areas during decision-making tasks. The goal was to understand why stress can tri…

This study looked at 70 women with severe menstrual pain to understand why some don't get relief from common painkillers like ibuprofen. Researchers measured pain sensitivity and brain processing to see if changes in the nervous system play a role. The goal is to identify women a…

This study looked at how people with opioid use disorder react to pain and whether that affects their craving for opioids. 89 adults with both opioid use disorder and chronic pain took part. They received a brief education session and then had their pain response and cravings mea…

This study involved 83 adults recently diagnosed with borderline personality disorder (BPD). Participants watched educational videos about BPD or other topics and completed daily surveys about their emotions and social interactions. The goal was to see if learning more about BPD …