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Brain scans may reveal best depression treatment

NCT ID NCT05537584

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This study aimed to find out which antidepressant works best for people with depression and loss of interest (anhedonia) by using brain scans and behavior tests. 133 adults with major depression took part. The goal was to predict the best treatment before starting medication, using brain activity and decision-making tasks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • McLean Hospital

    Belmont, Massachusetts, 02478, United States

Conditions

Explore the condition pages connected to this study.