Brain scans could predict which depression pill works best
NCT ID NCT05537584
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 27 times
Summary
This study aimed to find out if brain scans and simple behavior tests can help doctors choose the right antidepressant for people with depression who also have anhedonia (loss of interest or pleasure). 133 adults with major depression completed brain imaging and reward-based tasks before starting treatment. The goal was to see if these measures could predict who would respond best to which medication, making treatment more personalized and effective.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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McLean Hospital
Belmont, Massachusetts, 02478, United States
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