Mclean Hospital

This early-stage study aimed to see if a medication called lorcaserin could help people with cocaine dependence. Researchers planned to use brain scans to check if the drug could reduce reactions to drug cues and lower impulsive behavior. The study was withdrawn before any partic…

This early-stage study is testing whether a dietary supplement called nicotinamide riboside (a form of vitamin B3) can improve brain energy levels and slow cognitive decline. It involves 50 older adults with mild memory problems or early Alzheimer's disease. Researchers will use …

This small, early-stage study is testing whether a liquid CBD solution placed under the tongue can help reduce anxiety and agitation in older adults with mild memory problems or early Alzheimer's disease. The 12 participants will take the solution for eight weeks while researcher…

This study aims to understand how the brains of people who have recovered from major depression work when making simple approach or avoid decisions. Researchers will use MRI brain scans and computer tasks to see if they can find patterns that predict who might experience depressi…

This study aims to understand how childhood trauma affects the brain in women with PTSD or dissociative identity disorder. Researchers will use brain scans and genetic tests to look for biological links to dissociative symptoms. The study involves 200 women and includes follow-up…

This study aims to understand how a magnetic stimulation treatment affects the brain in older adults with bipolar depression. Researchers will use brain scans before and after treatment to measure changes in brain activity. The goal is to gather information that could help guide …

This study aimed to understand if a drug called LY-2940094 could protect healthy people from developing depression- and anxiety-like symptoms after stress. Researchers planned to give the drug to volunteers and then measure their brain's reward system and fear responses in a lab …