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Could CBD ease endometriosis pain? new trial aims to find out

NCT ID NCT06477406

First seen Apr 21, 2026 · Last updated Jun 22, 2026 · Updated 9 times

Summary

This phase 2 trial tests a custom high-CBD sublingual product against a placebo in 30 women with endometriosis. Over 12 weeks, researchers will measure changes in pain and quality of life. The goal is to see if cannabinoids can help manage symptoms where few proven options exist.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • McLean Hospital

    RECRUITING

    Belmont, Massachusetts, 02478, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

high-CBD hemp-derived sublingual solution

What this could lead to

If it works, this could point toward a new, non-drug option for managing endometriosis pain.

What could go wrong

This is a small early-phase trial with only 30 people, so results may not apply to everyone. It tests symptom relief, not a cure, and participants must stop using other cannabis products.

Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.