Could CBD ease endometriosis pain? new trial aims to find out

NCT ID NCT06477406

Recruiting now Symptom relief Sponsor: Mclean Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This phase 2 trial tests a custom high-CBD sublingual product against a placebo in 30 women with endometriosis. Over 12 weeks, researchers will measure changes in pain and quality of life. The goal is to see if cannabinoids can help manage symptoms where few proven options exist.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high-CBD hemp-derived sublingual solution
What this could lead to: If it works, this could point toward a new, non-drug option for managing endometriosis pain.
What could go wrong: This is a small early-phase trial with only 30 people, so results may not apply to everyone. It tests symptom relief, not a cure, and participants must stop using other cannabis products.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIOSIS

Contacts and locations

Locations

McLean Hospital
RECRUITING

Belmont, Massachusetts, 02478, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.