Massachusetts Eye And Ear Infirmary
Clinical trials sponsored by Massachusetts Eye And Ear Infirmary, explained in plain language.
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Common painkiller may fight rare brain tumors
Disease control OngoingThis study tests whether taking aspirin can slow the growth of vestibular schwannomas (non-cancerous brain tumors) and help preserve hearing. About 97 people with these tumors, including those with neurofibromatosis type 2, will receive either aspirin or a placebo. The goal is to…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated May 26, 2026 03:14 UTC
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New drug combo may help surgeons remove tough thyroid tumors
Disease control OngoingThis study tests whether giving the drug lenvatinib before surgery can help doctors more completely remove advanced thyroid cancer that has spread outside the gland. About 30 adults with this type of cancer will receive lenvatinib for a short time before their operation. The goal…
Phase: PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Could a common antibiotic shrink NF2 skin tumors without surgery?
Disease control OngoingThis study tests whether injecting doxycycline directly into skin tumors (schwannomas) can shrink them in people with neurofibromatosis type 2 (NF2). About 19 participants will receive the injections, and doctors will measure tumor size changes over time. The goal is to find a le…
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated May 18, 2026 12:10 UTC
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Special glasses could help Half-Blind people spot dangers
Symptom relief OngoingThis study tests two types of high-power prism glasses for people with homonymous hemianopia, a condition where half of the visual field is lost in both eyes. The goal is to see if these glasses help people detect hazards, like pedestrians, approaching from their blind side durin…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated May 26, 2026 03:19 UTC
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New training could help drivers with vision loss spot hazards
Symptom relief OngoingThis study tests a new training method for people with homonymous visual field loss (blindness in half of their vision). The training uses reminder cues to encourage larger head scans toward the blind side while driving. Researchers will measure how often participants make early …
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated May 26, 2026 03:13 UTC
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Virtual reality prisms could expand vision for people with tunnel vision
Symptom relief OngoingThis study tests a virtual reality headset that uses special prisms to expand the field of view for people with vision loss, such as tunnel vision or hemianopia. About 15 participants will walk in a real environment while the headset shows virtual pedestrians, and researchers wil…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Apr 30, 2026 15:52 UTC
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Eye stress test study pulled before it even started
Knowledge-focused TerminatedThis study aimed to compare how the cornea swells and recovers after wearing a contact lens in people with Fuchs' dystrophy versus healthy eyes. Researchers planned to measure corneal thickness changes over time. However, the study was withdrawn before enrolling any participants,…
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Knowledge-focused
Last updated May 26, 2026 03:06 UTC
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Promising tinnitus therapy study pulled before it began
Knowledge-focused TerminatedThis study planned to test a new sound therapy for people with tinnitus (ringing in the ears) and hyperacusis (sensitivity to sound). The therapy used a closed-loop system to retrain the brain. However, the study was withdrawn before enrolling any participants, so no results are …
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Hearing loss study pulled before starting: what was planned?
Knowledge-focused TerminatedThis study was withdrawn before enrolling any participants. It aimed to understand why older adults with high-frequency hearing loss struggle to hear speech in noisy places. Researchers planned to use a listening game to see if it could improve speech understanding, while trackin…
Phase: NA • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC