Massachusetts Eye And Ear Infirmary
Clinical trials sponsored by Massachusetts Eye And Ear Infirmary, explained in plain language.
Upcoming readouts
Trials from this sponsor expected to report results within the next 12 months.
- Could a simple eye drop stop blindness after retinal detachment? Results expected Sep 2026 (estimated)
- Could a common antibiotic shrink NF2 skin tumors without surgery? Results expected Sep 2026 (estimated)
- Cochlear implant study seeks to cut doctor visits without sacrificing hearing Results expected Nov 2026 (estimated)
- Could a probiotic help save sight in diabetes? Results expected Mar 2027 (estimated)
- New cochlear implant programming aims to sharpen hearing Results expected Mar 2027 (estimated)
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Could a single injection replace weeks of eye drops after retinal surgery?
Disease control CompletedThis study tests whether a steroid injection given during retinal detachment surgery can replace the usual course of antibiotic and steroid eye drops afterward. About 168 adults with a first-time retinal detachment will receive either the injection or standard drops. The goal is …
Phase 4 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Could a Pre-Surgery drug improve thyroid cancer outcomes?
Disease control CompletedThis study tested whether giving the drug lenvatinib before surgery helps remove advanced thyroid cancer more completely. 29 adults with invasive thyroid cancer took lenvatinib for a short time before their operation. The goal was to see if more patients could have clear or nearl…
Phase 2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Eye drop may prevent eyelash regrowth after trachoma surgery
Disease control CompletedThis study tested whether a steroid eye drop (fluorometholone) given for four weeks after trachoma surgery could stop eyelashes from growing back and rubbing against the eye. Over 2,400 people aged 15 and older took part. The goal was to see if this simple, low-cost addition to s…
Phase 3 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could an eye injection ease thyroid eye disease? small trial tests safety
Disease control CompletedThis Phase 2 trial tested whether injections of aflibercept, a drug that blocks abnormal blood vessel growth, are safe for people with active thyroid eye disease. Eleven adults received three injections over a month, with or without hyaluronidase to help spread the drug. The main…
Phase 2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Blood test shows promise for anal cancer screening
Diagnosis CompletedThis study tested a simple blood test to screen for anal dysplasia, a precancerous condition linked to HPV. Researchers enrolled 104 people with past or current anal HPV, plus some healthy controls. The goal was to see if the blood test could detect and classify anal dysplasia wi…
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Jun 27, 2026 12:25 UTC
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Blood test spots hidden cancer after surgery in HPV head & neck patients
Diagnosis CompletedThis study tested a new blood test (liquid biopsy) to see if it could find any cancer left behind after surgery in 103 people with HPV-related head and neck cancer. The goal was to catch remaining disease early, which could help doctors decide if more treatment is needed. The tes…
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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New training could help drivers with vision loss spot hazards
Symptom relief CompletedThis study tests a new training method for people who have lost part of their vision (homonymous hemianopia or quadrantanopia) to help them scan more effectively while driving. Sixteen participants will use reminder cues to practice making larger head scans toward their blind sid…
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Sep 20, 2026 00:00 UTC
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Prism glasses could help half-blind patients spot dangers
Symptom relief CompletedThis study tests two types of high-power prism glasses designed to expand the field of view for people with homonymous hemianopia, a condition where the same half of vision is missing in both eyes. About 64 participants will use the glasses while walking in a virtual reality simu…
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC