Ku Leuven

This study tests a program called I-CONNECT that coordinates care for older adults (65+) who have depression or bipolar disorder and at least two chronic physical conditions like diabetes or high blood pressure. Participants receive a personalized care plan, medication review, an…

This study tests whether a home-based breathing exercise program can reduce hospital readmissions and deaths in people recovering from a severe COPD flare-up. About 358 participants will either receive usual care or add daily inspiratory muscle training using a smartphone-connect…

This study tests a digital tool that gives doctors real-time, guideline-based advice on prescribing antibiotics. About 48 general practices in Belgium will use the tool during patient visits. The goal is to see if it reduces unnecessary antibiotic use and helps fight antibiotic r…

This study is testing a smartphone app that helps rectal cancer patients track their bowel symptoms after treatment. The goal is to create a better way to diagnose and manage these symptoms, which can be long-lasting. About 158 participants will use the app for a week and give fe…

This study tests a new, quick blood test done right in the emergency room to rule out heart attacks in people with chest pain. The goal is to see if this faster test can get patients discharged sooner compared to the usual lab test, which can take an hour or more. About 1,500 adu…

This study aims to improve how doctors tell the difference between borderline ovarian tumors and early-stage invasive ovarian cancer before surgery. Researchers will test a panel of nine blood-based biomarkers in 400 women with suspicious ovarian cysts. If successful, this could …

This study aims to see if certain chemicals (oncometabolites) in a person's breath and blood can spot early-stage gastro-esophageal cancer. Researchers will compare samples from 1,000 people, including those with cancer, those with Barrett's esophagus (a precancerous condition), …

This study tests whether using a fluid enriched with hyaluronan (a natural substance) during embryo transfer can help more women achieve a lasting pregnancy. About 400 women under 40 who have not had a successful pregnancy after previous IVF attempts will take part. The main goal…

This study looks at whether inhaling menthol can quickly relieve shortness of breath in healthy adults and people with COPD. Researchers will measure brain activity and breathing to understand how menthol works. The goal is to find a simple, drug-free way to ease breathing discom…

This study looks at whether a team-based rehab program called Revita can help people with long-term back or spine problems. About 90 adults will take part in exercise and therapy sessions. Researchers will measure changes in pain, daily function, and quality of life before and af…

This study looks at whether doing a 12-week exercise program with your feet turned outward (toes-out) helps people with mid-portion Achilles tendinopathy more than the usual neutral-foot position. About 60 adults aged 18–65 with Achilles pain will be followed for 6 months. Resear…

This study looks at whether taking CBD (a compound from cannabis) can improve sleep quality after doing intense exercise late in the evening. Twenty healthy adults will have their sleep monitored in a lab after taking either CBD or a placebo. The goal is to see if CBD helps peopl…

This study tests whether adding one hour of arm-hand exercises daily (5 days a week for 4 weeks) to usual care helps stroke patients regain arm function. 80 people who had a stroke within the last 5 months will be randomly assigned to either the extra arm-hand program or a lower-…

This small study in Uganda looks at how meals made with local fruits and vegetables affect blood sugar and fat levels in people with type 2 diabetes. Eight participants will eat five different test meals over five weeks, with blood samples taken over three hours after each meal. …

This study looks at whether special breathing exercises can help patients in the intensive care unit (ICU) who are having trouble weaning off a mechanical ventilator. Researchers will compare three approaches: usual care, high-intensity inspiratory muscle training, and a sham low…

This study follows 150 rectal cancer patients to understand why some have lasting bowel problems after treatment. Participants use a smartphone app to track symptoms and fill out quality-of-life questionnaires. The goal is to identify factors that lead to persistent issues, so do…

This study tests two ways of doing bed-cycling exercise in ICU patients who are on a ventilator. One method is steady cycling for 10-20 minutes, the other is short bursts of high-intensity cycling with rest periods. Researchers want to see which approach better activates leg musc…

This study takes small tissue samples from the rectum of people with irritable bowel syndrome (IBS) and healthy volunteers to measure how the nerves in the gut are working. Researchers will use special imaging and other lab techniques to see how these nerves respond to different …

After a stroke, many people struggle to use both hands together. This study checks if a new test called the Ad-AHA Stroke accurately measures how people actually use their hands in daily life. Thirty-two stroke survivors will wear wrist sensors for three days while their hand use…

This study tests an artificial intelligence algorithm that uses wearable sensors to detect freezing of gait—a sudden inability to walk—in people with Parkinson's disease. Researchers want to see if the AI works accurately in home environments, not just in the lab. About 126 parti…

This study uses a 20-25 minute survey to find out which features of diagnostic tests for gastro-esophageal cancer matter most to patients and the general public. Researchers aim to understand preferences and regional differences to improve screening decisions. About 2,200 adults …

This study looks at different forms of IgE (a protein involved in allergic reactions) in healthy volunteers and people with conditions like severe allergies, chronic hives, mastocytosis, and immune deficiencies. Researchers aim to understand how these IgE variations relate to hea…

This study aims to improve how doctors monitor chronic lung diseases by using a computer model to predict changes in lung function. Researchers will collect data from 4,000 adults with chronic respiratory conditions to see if the model can accurately forecast lung function and id…

This study checks if a new smartphone-based method called ESDAM can accurately measure daily food and drink intake. Researchers will compare ESDAM results with objective lab tests in 115 healthy adults. The goal is to see if this app can be a reliable tool for future nutrition re…