Jagiellonian University

This study tests whether giving a medicine called noradrenaline through a vein during surgery can prevent dangerous drops in blood pressure better than usual care. About 750 adults aged 45 and older having non-cardiac surgery will take part. The goal is to see if this approach re…

This study compares two surgical options for people with severe obesity and acid reflux (GERD). Half of the 560 participants will get a newer procedure called Nissen-Sleeve Gastrectomy, which combines stomach reduction with a reflux barrier; the other half will get the standard R…

This study tests whether avoiding opioid painkillers during major urologic surgery leads to better recovery. About 200 adults will be randomly assigned to receive either opioid-free anesthesia (using other drugs) or standard opioid-based anesthesia. The main goal is to see how pa…

This study compares opioid-free anesthesia to standard opioid anesthesia in 200 adults undergoing pancreatic surgery. The goal is to see if avoiding opioids during surgery can still control pain well and reduce the need for painkillers afterward. Participants will have their pain…

This study compares opioid-free anesthesia to standard opioid-based anesthesia for people having laparoscopic pancreatic surgery. The goal is to see if avoiding opioids leads to less pain and lower opioid use after surgery. Two hundred adults aged 18-80 will take part, and resear…

This study compares opioid-free anesthesia to standard opioid-based anesthesia in 600 adults undergoing urological abdominal surgery. The goal is to see if avoiding opioids during surgery reduces the need for painkillers afterward and lowers side effects like nausea. Patients wil…

This study looks at inflammation markers in the blood of women with PCOS, with or without insulin resistance, and compares them to women without PCOS. The goal is to understand how inflammation relates to metabolic problems in PCOS. Participants will have blood tests but no treat…

This study is measuring three proteins (kisspeptin, ghrelin, and zonulin) in the blood of women with and without PCOS to see if they can serve as early warning signs of insulin resistance. Researchers will compare levels among three groups: women with PCOS and insulin resistance,…

This study looks at three hormones (leptin, resistin, omentin-1) in women with PCOS, with or without insulin resistance, and compares them to women without PCOS. The goal is to better understand how these hormones relate to metabolic health. No treatments or interventions are giv…

This study looks at immune cells in the womb lining and blood of women with unexplained infertility or repeated miscarriages, compared to fertile women. Researchers want to see if differences in these cells help explain why some women have trouble getting pregnant. The study invo…

This study looks at how urological diseases and their treatments impact patients' work life. Researchers will survey 2,000 adults admitted to a hospital in Poland, focusing on those having major cancer surgeries or stone procedures. Participants will be followed for 6 months to t…

This study looks at how common post-traumatic stress disorder (PTSD) symptoms are in women who have had a miscarriage in the first three months of pregnancy. Researchers will use questionnaires to measure symptoms and recovery stages. The goal is to better identify women who coul…

This study looks at how many women experience post-traumatic stress disorder (PTSD) symptoms after being diagnosed with an ectopic pregnancy. Researchers will use questionnaires to measure symptoms and recovery stages in 200 women. The goal is to better identify those who might n…

This study looks at how blood clots form and break down in women after surgery for uterine prolapse or urine incontinence. Researchers will measure clot properties and thrombin generation in 60 women aged 18-70 who did not improve with medication. The goal is to better understand…

This study looks at how blood clotting changes in pregnant women and whether these changes can predict complications like blood clots or high blood pressure. Researchers will study 100 women aged 18-40 with natural pregnancies. The goal is to use machine learning to find hidden r…

This study looks at how different ovarian stimulation protocols affect blood clotting in 300 infertile women, including those with endometriosis. Researchers will measure clot formation and breakdown before and after treatment. The goal is to understand which protocols may be saf…