Could a simple blood test spot insulin trouble early in PCOS?
NCT ID NCT06793098
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is measuring three proteins (kisspeptin, ghrelin, and zonulin) in the blood of women with and without PCOS to see if they can serve as early warning signs of insulin resistance. Researchers will compare levels among three groups: women with PCOS and insulin resistance, women with PCOS but no insulin resistance, and women without PCOS. The goal is to find a simple blood test that could help detect metabolic problems earlier.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test to detect insulin resistance early in women with PCOS.
- What could go wrong
- This is an early observational study with only 100 participants. The proteins measured may not prove to be reliable markers, and results may not apply to all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
women aged 18-45 years managed for menstrual irregularities or for routine check-up
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * women aged 18-45 years Exclusion Criteria: * removal of at least one ovary * treated diabetes of any type * diagnosed and treated metabolic diseases * diagnosed and treated autoimmune diseases * diagnosed and treated autoinflammatory diseases
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jagiellonian University
RECRUITINGKrakow, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a supplement duo quiet PCOS-Linked inflammation?
- Steak solution? lean beef may tame blood sugar in teens with PCOS
- Can diet plus inositol or metformin tame insulin resistance in PCOS?
- Can a gut microbiome transplant boost fertility in PCOS?
- A simple blood test may flag hidden insulin problems in PCOS
- Can tracking PCOS over time unlock better care?