PCOS (POLYCYSTIC OVARY SYNDROME)

This study tests whether taking letrozole for 10 days instead of the usual 5 days helps more women with PCOS ovulate and get pregnant. About 84 women aged 18-40 will be randomly assigned to one of two groups. The main goal is to see if the longer treatment leads to more ovulation…

This study is testing a 6-month low-glycemic, high-fiber diet in 56 women with PCOS living in remote Yunnan, China. The goal is to see if this culturally-adapted diet can improve insulin resistance, hormone levels, and menstrual regularity. Participants must have a BMI of 24 or h…

This study tests whether online group education and lifestyle support can improve quality of life and health in women with PCOS and obesity. Forty non-pregnant women aged 18-49 with PCOS and a BMI of 30 or higher will join virtual sessions or a control group. Researchers will mea…

This 12-week study at Ohio State University tests whether a keto diet or a mixed diet with ketone supplements can help women with PCOS have more regular periods and improve hormone balance. About 40 women aged 18-40 with PCOS will be randomly assigned to one of two groups. The go…

This study tests if two natural supplements, Myo-Inositol and Dioscorea Villosa, can help teenagers aged 14-19 get regular menstrual cycles. It includes teens with or without PCOS who have periods that are too short, too long, or absent. The goal is to see if more teens have a no…

This study looks at whether a physical activity program can help improve hormone health and reduce diabetes risk in girls ages 8 to 12 who may be at higher risk for PCOS. Participants will either get a full program with coaching and messages or a lower-intensity version with mess…

This pilot study looks at gene activity in cumulus cells (support cells around eggs) from 10 women with PCOS undergoing a special lab-based egg maturation technique called CAPA-IVM. Researchers aim to find if these gene patterns can predict which eggs will develop into healthy em…

This study looks at inflammatory substances in the blood of women with PCOS, with or without insulin resistance, compared to women without PCOS. Researchers want to see if certain inflammation markers are linked to metabolic problems. No treatments are given; the goal is to bette…

This study looks at three proteins (kisspeptin, ghrelin, zonulin) in the blood of women with PCOS to see if they can serve as early warning signs for insulin resistance. Researchers will compare protein levels among women with PCOS and insulin resistance, women with PCOS but no i…